Julio A. Gutierrez, Andres F. Carrion, Danny Avalos, Christopher O'Brien, Paul Martin, Kalyan Ram Bhamidimarri, Adam Peyton – 30 March 2015 – Recurrent hepatitis C virus (HCV) infection occurs universally in the allograft in the absence of effective antiviral therapy before liver transplantation (LT). Antiviral therapy with sofosbuvir and simeprevir has proven to be highly effective and well tolerated in the nontransplant setting for treatment of HCV genotype 1 infection; therefore, we sought to evaluate the efficacy and safety of this regimen in LT recipients with recurrent HCV infection.

Laia Tolosa, Silvia López, Eugenia Pareja, María Teresa Donato, Anne Myara, Tuan Huy Nguyen, José Vicente Castell, María José Gómez‐Lechón – 30 March 2015 – Crigler‐Najjar type 1 disease is a rare inherited metabolic disease characterized by high levels of unconjugated bilirubin due to the complete absence of hepatic uridine diphosphoglucuronate–glucuronosyltransferase activity. Hepatocyte transplantation (HT) has been proposed as an alternative treatment for Crigler‐Najjar syndrome, but it is still limited by the quality and the low engraftment and repopulation ability of the cells used.

Giammauro Berardi, Federico Tomassini, Roberto Ivan Troisi – 30 March 2015 – Living donor liver transplantation is a valid alternative to deceased donor liver transplantation, and its safety and feasibility have been well determined. Minimally invasive living donor hepatectomy (MILDH) has taken some time to be accepted because of inherent technical difficulties and the highly demanding surgical skills needed to perform the procedure, and its role is still being debated.

Akihiko Soyama, Mitsuhisa Takatsuki, Masaaki Hidaka, Hajime Imamura, Tamotsu Kuroki, Susumu Eguchi – 30 March 2015

Priya Handa, Kris V. Kowdley – 29 March 2015

Helga Mogensen, Einar S. Björnsson – 29 March 2015

Helga Mogensen, Einar S. Björnsson – 29 March 2015

Jasmohan S. Bajaj, Naga S. Betrapally, Phillip B. Hylemon, Douglas M. Heuman, Kalyani Daita, Melanie B. White, Ariel Unser, Leroy R. Thacker, Arun J. Sanyal, Dae Joong Kang, Masoumeh Sikaroodi, Patrick M Gillevet – 29 March 2015 – Altered gut microbiome is associated with systemic inflammation and cirrhosis decompensation. However, the correlation of the oral microbiome with inflammation in cirrhosis is unclear. Our aim was to evaluate the oral microbiome in cirrhosis and compare with stool microbiome.

Karim J. Halazun, Rachel E. Patzer, Abbas A. Rana, Benjamin Samstein, Robert S. Brown, Jean C. Emond – 29 March 2015

Kuang‐Hsiang Chuang, Christa L. Whitney‐Miller, Chin‐Yi Chu, Zhongren Zhou, M. Katherine Dokus, Shannon Schmit, Christopher T. Barry – 29 March 2015 – Vascular invasion provides a direct route for tumor metastasis. The degree to which microRNA (miRNA) expression plays a role in tumor vascular invasion is unclear. Here, we report that miR‐494 is up‐regulated in human hepatocellular carcinoma (HCC) tumors with vascular invasion and can promote HCC cell invasiveness by gene inactivation of multiple invasion‐suppressor miRNAs.