MicroRNA/gene profiling unveils early molecular changes and nuclear factor erythroid related factor 2 (NRF2) activation in a rat model recapitulating human hepatocellular carcinoma (HCC)

Annalisa Petrelli, Andrea Perra, Davide Cora, Pia Sulas, Silvia Menegon, Claudia Manca, Cristina Migliore, Marta Anna Kowalik, Giovanna Maria Ledda‐Columbano, Silvia Giordano, Amedeo Columbano – 15 July 2013 – Studies on gene and/or microRNA (miRNA) dysregulation in the early stages of hepatocarcinogenesis are hampered by the difficulty of diagnosing early lesions in humans. Experimental models recapitulating human hepatocellular carcinoma (HCC) are then used to perform this analysis.

Association of severe intrahepatic cholestasis of pregnancy with adverse pregnancy outcomes: A prospective population‐based case‐control study

Victoria Geenes, Lucy C. Chappell, Paul T. Seed, Philip J. Steer, Marian Knight, Catherine Williamson – 15 July 2013 – Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy‐specific liver disease, characterized by maternal pruritus and raised serum bile acids. Our objectives were to describe the epidemiology and pregnancy complications associated with severe ICP and to test the hypothesis that adverse perinatal outcomes are increased in these women.

Radiologic course of primary sclerosing cholangitis: Assessment by three‐dimensional magnetic resonance cholangiography and predictive features of progression

Ana Ruiz, Sara Lemoinne, Fabrice Carrat, Christophe Corpechot, Olivier Chazouillères, Lionel Arrivé – 15 July 2013 – Magnetic resonance imaging (MRI) with magnetic resonance cholangiography (MRC) has become the radiologic standard of reference for diagnosis of primary sclerosing cholangitis (PSC). However, natural history of radiologic features of PSC is poorly known. In the current study, we aimed at analyzing the course of PSC using three‐dimensional (3D) MRC and liver MRI to find predictive radiologic features of progression.

Radiologic course of primary sclerosing cholangitis: Assessment by three‐dimensional magnetic resonance cholangiography and predictive features of progression

Ana Ruiz, Sara Lemoinne, Fabrice Carrat, Christophe Corpechot, Olivier Chazouillères, Lionel Arrivé – 15 July 2013 – Magnetic resonance imaging (MRI) with magnetic resonance cholangiography (MRC) has become the radiologic standard of reference for diagnosis of primary sclerosing cholangitis (PSC). However, natural history of radiologic features of PSC is poorly known. In the current study, we aimed at analyzing the course of PSC using three‐dimensional (3D) MRC and liver MRI to find predictive radiologic features of progression.

Randomized, double‐blind, controlled study of glycerol phenylbutyrate in hepatic encephalopathy

Don C. Rockey, John M. Vierling, Parvez Mantry, Marwan Ghabril, Robert S. Brown, Olga Alexeeva, Igor A. Zupanets, Vladimir Grinevich, Andrey Baranovsky, Larysa Dudar, Galyna Fadieienko, Nataliya Kharchenko, Iryna Klaryts'ka, Vyacheslav Morozov, Priya Grewal, Timothy McCashland, K. Gautham Reddy, K. Rajender Reddy, Vasyl Syplyviy, Nathan M. Bass, Klara Dickinson, Catherine Norris, Dion Coakley, Masoud Mokhtarani, Bruce F.

Left ventricular dysfunction in obese children and adolescents with nonalcoholic fatty liver disease

Lucia Pacifico, Michele Di Martino, Antonio De Merulis, Mario Bezzi, John Frederick Osborn, Carlo Catalano, Claudio Chiesa – 11 July 2013 – Nonalcoholic fatty liver disease (NAFLD) may increase the risk for cardiac dysfunction. The present study aimed to determine whether, in children, NAFLD is associated with subclinical left ventricular (LV) structural and functional abnormalities independently of metabolic risk factors.

Left ventricular dysfunction in obese children and adolescents with nonalcoholic fatty liver disease

Lucia Pacifico, Michele Di Martino, Antonio De Merulis, Mario Bezzi, John Frederick Osborn, Carlo Catalano, Claudio Chiesa – 11 July 2013 – Nonalcoholic fatty liver disease (NAFLD) may increase the risk for cardiac dysfunction. The present study aimed to determine whether, in children, NAFLD is associated with subclinical left ventricular (LV) structural and functional abnormalities independently of metabolic risk factors.

Randomized, double‐blind, controlled study of glycerol phenylbutyrate in hepatic encephalopathy

Don C. Rockey, John M. Vierling, Parvez Mantry, Marwan Ghabril, Robert S. Brown, Olga Alexeeva, Igor A. Zupanets, Vladimir Grinevich, Andrey Baranovsky, Larysa Dudar, Galyna Fadieienko, Nataliya Kharchenko, Iryna Klaryts'ka, Vyacheslav Morozov, Priya Grewal, Timothy McCashland, K. Gautham Reddy, K. Rajender Reddy, Vasyl Syplyviy, Nathan M. Bass, Klara Dickinson, Catherine Norris, Dion Coakley, Masoud Mokhtarani, Bruce F.

Subscribe to