Randomized, double‐blind, controlled study of glycerol phenylbutyrate in hepatic encephalopathy

Don C. Rockey, John M. Vierling, Parvez Mantry, Marwan Ghabril, Robert S. Brown, Olga Alexeeva, Igor A. Zupanets, Vladimir Grinevich, Andrey Baranovsky, Larysa Dudar, Galyna Fadieienko, Nataliya Kharchenko, Iryna Klaryts'ka, Vyacheslav Morozov, Priya Grewal, Timothy McCashland, K. Gautham Reddy, K. Rajender Reddy, Vasyl Syplyviy, Nathan M. Bass, Klara Dickinson, Catherine Norris, Dion Coakley, Masoud Mokhtarani, Bruce F.

Left ventricular dysfunction in obese children and adolescents with nonalcoholic fatty liver disease

Lucia Pacifico, Michele Di Martino, Antonio De Merulis, Mario Bezzi, John Frederick Osborn, Carlo Catalano, Claudio Chiesa – 11 July 2013 – Nonalcoholic fatty liver disease (NAFLD) may increase the risk for cardiac dysfunction. The present study aimed to determine whether, in children, NAFLD is associated with subclinical left ventricular (LV) structural and functional abnormalities independently of metabolic risk factors.

Left ventricular dysfunction in obese children and adolescents with nonalcoholic fatty liver disease

Lucia Pacifico, Michele Di Martino, Antonio De Merulis, Mario Bezzi, John Frederick Osborn, Carlo Catalano, Claudio Chiesa – 11 July 2013 – Nonalcoholic fatty liver disease (NAFLD) may increase the risk for cardiac dysfunction. The present study aimed to determine whether, in children, NAFLD is associated with subclinical left ventricular (LV) structural and functional abnormalities independently of metabolic risk factors.

Randomized, double‐blind, controlled study of glycerol phenylbutyrate in hepatic encephalopathy

Don C. Rockey, John M. Vierling, Parvez Mantry, Marwan Ghabril, Robert S. Brown, Olga Alexeeva, Igor A. Zupanets, Vladimir Grinevich, Andrey Baranovsky, Larysa Dudar, Galyna Fadieienko, Nataliya Kharchenko, Iryna Klaryts'ka, Vyacheslav Morozov, Priya Grewal, Timothy McCashland, K. Gautham Reddy, K. Rajender Reddy, Vasyl Syplyviy, Nathan M. Bass, Klara Dickinson, Catherine Norris, Dion Coakley, Masoud Mokhtarani, Bruce F.

Repopulation of the fibrotic/cirrhotic rat liver by transplanted hepatic stem/progenitor cells and mature hepatocytes

Mladen I. Yovchev, Yuhua Xue, David A. Shafritz, Joseph Locker, Michael Oertel – 10 July 2013 – Considerable progress has been made in developing antifibrotic agents and other strategies to treat liver fibrosis; however, significant long‐term restoration of functional liver mass has not yet been achieved. Therefore, we investigated whether transplanted hepatic stem/progenitor cells can effectively repopulate the liver with advanced fibrosis/cirrhosis.

Relationship between the histological appearance of the portal vein and development of ischemic‐type biliary lesions after liver transplantation

Waqar R. R. Farid, Jeroen Jonge, Pieter E. Zondervan, Ahmet Demirkiran, Herold J. Metselaar, Hugo W. Tilanus, Ron W. F. Bruin, Luc J. W. Laan, Geert Kazemier – 10 July 2013 – Ischemic‐type biliary lesions (ITBLs) are a major cause of morbidity after liver transplantation (LT). Their assumed underlying pathophysiological mechanism is ischemia/reperfusion injury of the biliary tree, in which the portal circulation has been proposed recently to have a role.

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