Rabindranath Bera, Chih‐Yung Chiou, Ming‐Chin Yu, Jei‐Ming Peng, Chung‐Ru He, Chih‐Yun Hsu, Hsiao‐Ling Huang, Uda Y. Ho, Shi‐Ming Lin, Yu‐Jr Lin, Sen‐Yung Hsieh – 27 January 2014 – It is unclear how proliferating cells elicit suppression on cell proliferation and how cancer cells evade this growth suppression.
Timucin Taner, Mark D. Stegall, Julie K. Heimbach – 27 January 2014 – Interest in the role of donor‐specific human leukocyte antibodies in liver transplantation has been rekindled recently. Emerging evidence suggests that these antibodies may cause injury to the liver allograft. Here we review the clinical literature, highlight controversial results, and propose a path forward for the definition and better understanding of antibody‐mediated injury to the liver. Liver Transpl 20:514–527, 2014. © 2014 AASLD.
Michael E. Sutton, Rico D. Bense, Ton Lisman, Eric J. Jagt, Aad P. Berg, Robert J. Porte – 24 January 2014 – There is no consensus on the preferred type of biliary reconstruction for patients undergoing orthotopic liver transplantation (OLT) for primary sclerosing cholangitis (PSC). The aim of this study was to compare long‐term outcomes after OLT for PSC using either duct‐to‐duct anastomosis or Roux‐en‐Y hepaticojejunostomy for biliary reconstruction.
Shohei Yoshiya, Toru Ikegami, Tomoharu Yoshizumi, Huanlin Wang, Noboru Harada, Yo‐Ichi Yamashita, Akihiro Nishie, Ken Shirabe, Yoshinao Oda, Yoshihiko Maehara – 23 January 2014
Jordi Gracia‐Sancho, Virginia Hernández‐Gea, Juan Carlos Garcia‐Pagán – 22 January 2014
Edoardo G. Giannini, R. Todd Stravitz, Stephen H. Caldwell – 22 January 2014
Martina Panattoni, Laura Maiorino, Anna Lukacs, Lorena Zentilin, Davide Mazza, Francesca Sanvito, Giovanni Sitia, Luca G. Guidotti, Ruggero Pardi – 22 January 2014 – Aberrant DNA replication induced by deregulated or excessive proliferative stimuli evokes a “replicative stress response” leading to cell cycle restriction and/or apoptosis. This robust fail‐safe mechanism is eventually bypassed by transformed cells, due to ill‐defined epistatic interactions.
Nicolas Lanthier, Isabelle A. Leclercq – 22 January 2014
Nils Jedicke, Nina Struever, Nupur Aggrawal, Tobias Welte, Michael P. Manns, Nisar P. Malek, Lars Zender, Sabina Janciauskiene, Torsten Wuestefeld – 21 January 2014 – Acute liver failure remains a critical clinical condition, with high mortality rates, and increased apoptosis of hepatocytes represents a key event in the cause of liver failure. Alpha‐1‐antitrypsin (AAT) is synthesized and secreted mainly by hepatocytes, and plasma purified AAT is used for augmentation therapy in patients with AAT deficiency.
Laura Milazzo, Anna Maria Peri, Lucia Lodi, Guido Gubertini, Anna Lisa Ridolfo, Spinello Antinori – 21 January 2014 – Primary intestinal lymphangiectasia (PIL) is a protein‐losing enteropathy characterized by tortuous and dilated lymph channels of the small bowel. The main symptoms are bilateral lower limb edema, serosal effusions, and vitamin D malabsorption resulting in osteoporosis. We report here a case of long‐lasting misdiagnosed PIL with a peculiar liver picture, characterized by a very high stiffness value at transient elastography, which decreased with clinical improvement.