Inferior survival in liver transplant recipients with hepatocellular carcinoma receiving donation after cardiac death liver allografts

Kris P. Croome, William Wall, Natasha Chandok, Gavin Beck, Paul Marotta, Roberto Hernandez‐Alejandro – 1 August 2013 – The impact of ischemia/reperfusion injury in the setting of transplantation for hepatocellular carcinoma (HCC) has not been thoroughly investigated. The present study examined data from the Scientific Registry of Transplant Recipients for all recipients of deceased donor liver transplants performed between January 1, 1995 and October 31, 2011.

Testosterone perturbs systemic iron balance through activation of epidermal growth factor receptor signaling in the liver and repression of hepcidin

Chloé Latour, Léon Kautz, Céline Besson‐Fournier, Marie‐Laure Island, François Canonne‐Hergaux, Olivier Loréal, Tomas Ganz, Hélène Coppin, Marie‐Paule Roth – 1 August 2013 – Gender‐related disparities in the regulation of iron metabolism may contribute to the differences exhibited by men and women in the progression of chronic liver diseases associated with reduced hepcidin expression, e.g., chronic hepatitis C, alcoholic liver disease, or hereditary hemochromatosis. However, their mechanisms remain poorly understood.

Increased hepatic stiffness as consequence of high hepatic afterload in the fontan circulation: A vascular doppler and elastography study

Shaija S. Kutty, Qinghai Peng, David A. Danford, Scott E. Fletcher, Deborah Perry, Geoffrey A. Talmon, Cynthia Scott, John D. Kugler, Kim F. Duncan, Ruben E. Quiros‐Tejeira, Shelby Kutty, the Liver Adult‐Pediatric‐Congenital‐Heart‐Disease Dysfunction Study (LADS) Group – 31 July 2013 – Hepatic dysfunction is a recognized complication after Fontan palliation of congenital heart disease. We sought to quantitatively measure hepatic stiffness and vascular Doppler indices using ultrasound (US) and shear wave elastography (SWE) in a Fontan cohort.

Exposure to ionizing radiation during liver transplantation evaluation, waitlist time, and in the postoperative period: A cause for concern

Ser Yee Lee, Michael A. Mooney, Matthew L. Inra, Krishna Juluru, Alyson N. Fox, Sonja K. Olsen, Robert S. Brown, Jean C. Emond, Daniel Cherqui, Michael D. Kluger – 31 July 2013 – Substantial evidence has linked ionizing radiation exposure (RE) to oncogenesis. Patients evaluated for transplantation undergo extensive diagnostic imaging and have increased baseline cancer risk factors. The objective was to examine exposure in a cohort of patients undergoing evaluation and liver transplantation. Radiation exposure from all diagnostic examinations and procedures were retrospectively recorded.

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