Identification of a novel biomarker gene set with sensitivity and specificity for distinguishing between allograft rejection and tolerance

Lin Xie, Naotsugu Ichimaru, Miwa Morita, Jiajie Chen, Ping Zhu, Jihong Wang, Peter Urbanellis, Itay Shalev, Shizuko Nagao, Atsushi Sugioka, Liang Zhong, Norio Nonomura, Shiro Takahara, Gary A. Levy, Xiao‐Kang Li – 7 December 2011 – Here we examined whether the expression of a novel immunoregulatory gene set could be used to predict outcomes in murine models of rapamycin‐induced cardiac tolerance, spontaneous hepatic tolerance, and cardiac rejection.

Split liver transplantation using extended right grafts: The natural history of segment 4 and its impact on early postoperative outcomes

Ailton Sepulveda, Olivier Scatton, Hadrien Tranchart, Hervé Gouya, Fabiano Perdigao, Fabien Stenard, Denis Bernard, Filomena Conti, Yvon Calmus, Olivier Soubrane – 6 December 2011 – Split liver transplantation (SLT) using extended right grafts is associated with complications related to ischemia of hepatic segment 4 (S4), and these complications are associated with poor outcomes. We retrospectively analyzed 36 SLT recipients so that we could assess the association of radiological, biological, and clinical features with S4 ischemia.

Impact of neoadjuvant chemoradiation on the tumor burden before liver transplantation for unresectable cholangiocarcinoma

Chakri Panjala, Justin H. Nguyen, Ali N. Al‐Hajjaj, Barry A. Rosser, Raouf E. Nakhleh, Mellena D. Bridges, Stephen J. Ko, Steven J. Buskirk, George P. Kim, Denise M. Harnois – 5 December 2011 – The very early experience with liver transplantation (LT) for cholangiocarcinoma (CC) was dismal because of the poor survival outcomes and the high recurrence rates. However, LT for CC in conjunction with neoadjuvant chemoradiation recently has shown encouraging results, although the data are extremely limited.

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