Identification of a novel biomarker gene set with sensitivity and specificity for distinguishing between allograft rejection and tolerance

Lin Xie, Naotsugu Ichimaru, Miwa Morita, Jiajie Chen, Ping Zhu, Jihong Wang, Peter Urbanellis, Itay Shalev, Shizuko Nagao, Atsushi Sugioka, Liang Zhong, Norio Nonomura, Shiro Takahara, Gary A. Levy, Xiao‐Kang Li – 7 December 2011 – Here we examined whether the expression of a novel immunoregulatory gene set could be used to predict outcomes in murine models of rapamycin‐induced cardiac tolerance, spontaneous hepatic tolerance, and cardiac rejection.

Split liver transplantation using extended right grafts: The natural history of segment 4 and its impact on early postoperative outcomes

Ailton Sepulveda, Olivier Scatton, Hadrien Tranchart, Hervé Gouya, Fabiano Perdigao, Fabien Stenard, Denis Bernard, Filomena Conti, Yvon Calmus, Olivier Soubrane – 6 December 2011 – Split liver transplantation (SLT) using extended right grafts is associated with complications related to ischemia of hepatic segment 4 (S4), and these complications are associated with poor outcomes. We retrospectively analyzed 36 SLT recipients so that we could assess the association of radiological, biological, and clinical features with S4 ischemia.

Exercise capacity and muscle strength in patients with cirrhosis

Jacqueline C. Jones, Jeff S. Coombes, Graeme A. Macdonald – 5 December 2011 – Exercise capacity and muscle strength are predictors of outcome in a number of clinical populations. Advanced liver disease is a catabolic state, and patients often have muscle wasting. However, the relationships between exercise capacity, strength, and outcomes for patients undergoing liver transplantation are poorly understood.

Is a mandatory intensive care unit stay needed after liver transplantation? Feasibility of fast‐tracking to the surgical ward after liver transplantation

C. Burcin Taner, Darrin L. Willingham, Ilynn G. Bulatao, Timothy S. Shine, Prith Peiris, Klaus D. Torp, Juan Canabal, Justin H. Nguyen, David J. Kramer – 5 December 2011 – The continuation of hemodynamic, respiratory, and metabolic support for a variable period after liver transplantation (LT) in the intensive care unit (ICU) is considered routine by many transplant programs. However, some LT recipients may be liberated from mechanical ventilation shortly after the discontinuation of anesthesia.

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