Clinical yield of diagnostic endoscopic retrograde cholangiopancreatography in orthotopic liver transplant recipients With suspected biliary complications

B. Joseph Elmunzer, Anthony T. DeBenedet, Michael L. Volk, Christopher J. Sonnenday, Akbar K. Waljee, Robert J. Fontana, Aarti B. Oza, Amit Singal, Michael J. Englesbe, James M. Scheiman – 10 August 2012 – Diagnostic endoscopic retrograde cholangiopancreatography (D‐ERCP) is commonly performed for the evaluation of biliary complications after orthotopic liver transplantation (OLT). This practice is contrary to the national trend of reserving endoscopic retrograde cholangiopancreatography (ERCP) for therapeutic purposes.

Progressive graft fibrosis and donor‐specific human leukocyte antigen antibodies in pediatric late liver allografts

Aya Miyagawa‐Hayashino, Atushi Yoshizawa, Yoichiro Uchida, Hiroto Egawa, Kimiko Yurugi, Satohiro Masuda, Sachiko Minamiguchi, Taira Maekawa, Shinji Uemoto, Hironori Haga – 10 August 2012 – The role of donor‐specific anti‐human leukocyte antigen antibodies (DSAs) that develop late after living donor liver transplantation is unknown. Seventy‐nine pediatric recipients who had good graft function and underwent protocol liver biopsy more than 5 years after transplantation (median = 11 years, range = 5‐20 years) were reviewed.

Intravenous N‐acetylcysteine in pediatric patients with nonacetaminophen acute liver failure: A placebo‐controlled clinical trial

Robert H. Squires, Anil Dhawan, Estella Alonso, Michael R. Narkewicz, Benjamin L. Shneider, Norberto Rodriguez‐Baez, Dominic Dell Olio, Saul Karpen, John Bucuvalas, Steven Lobritto, Elizabeth Rand, Philip Rosenthal, Simon Horslen, Vicky Ng, Girish Subbarao, Nanda Kerkar, David Rudnick, M. James Lopez, Kathleen Schwarz, Rene Romero, Scott Elisofon, Edward Doo, Patricia R. Robuck, Sharon Lawlor, Steven H.

Predictors of early graft survival after pediatric liver transplantation

Ruben Ciria, Diego Davila, Shirin E. Khorsandi, Faisal Dar, Roberto Valente, Javier Briceño, Hector Vilca‐Melendez, Anil Dhawan, Mohamed Rela, Nigel D. Heaton – 10 August 2012 – The objective of this study was to identify peritransplant predictors of early graft survival and posttransplant parameters that could be used to predict early graft outcomes after pediatric liver transplantation (PLT). The response of children to liver dysfunction after liver transplantation (LT) is poor.

Hepatic encephalopathy is associated with decreased cerebral oxygen metabolism and blood flow, not increased ammonia uptake

Gitte Dam, Susanne Keiding, Ole L. Munk, Peter Ott, Hendrik Vilstrup, Lasse K. Bak, Helle S. Waagepetersen, Arne Schousboe, Michael Sørensen – 10 August 2012 – Studies have shown decreased cerebral oxygen metabolism (CMRO2) and blood flow (CBF) in patients with cirrhosis with hepatic encephalopathy (HE). It remains unclear, however, whether these disturbances are associated with HE or with cirrhosis itself and how they may relate to arterial blood ammonia concentration and cerebral metabolic rate of blood ammonia (CMRA).

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