Anita Pathil, Jan Mueller, Arne Warth, Walee Chamulitrat, Wolfgang Stremmel – 20 December 2011 – Hepatic fat accumulation and changes in lipid composition are hallmarks of nonalcoholic fatty liver disease (NAFLD). As an experimental approach for treatment of NAFLD, we synthesized the bile acid–phospholipid conjugate ursodeoxycholyl lysophosphatidylethanolamide (UDCA‐LPE). Previous work demonstrated profound hepatoprotective properties of the conjugate in vitro and in vivo. Here we investigated the effects of UDCA‐LPE in two nutritional mouse models of NAFLD.

Douglas Dieterich – 16 December 2011

Ting Wu, Feng‐Cai Zhu, Shou‐Jie Huang, Xue‐Feng Zhang, Zhong‐Ze Wang, Jun Zhang, Ning‐Shao Xia – 13 December 2011

Marc G. Ghany, David R. Nelson, Doris B. Strader, David L. Thomas, Leonard B. Seeff – 12 December 2011

Eric Trepo, Erwan Guyot, Nathalie Ganne‐Carrie, Delphine Degre, Thierry Gustot, Denis Franchimont, Angela Sutton, Pierre Nahon, Christophe Moreno – 12 December 2011

Laura Milazzo, Antonella Foschi, Spinello Antinori – 12 December 2011

Heike Bantel, Matthias J. Bahr, Jerome Schlue, Klaus Schulze‐Osthoff – 12 December 2011

Ping Lam, Shuhua Xu, Carol J. Soroka, James L. Boyer – 12 December 2011 – The liver‐specific bile salt export pump (BSEP) is crucial for bile acid–dependent bile flow at the apical membrane. BSEP, a member of the family of structurally related adenosine triphosphate (ATP)‐binding cassette (ABC) proteins, is composed of 12 transmembrane segments (TMS) and two large cytoplasmic nucleotide‐binding domains (NBDs).

Yusuf Yilmaz, Ramazan Kurt – 12 December 2011

Bryan Cobb, Regis A. Vilchez – 12 December 2011