Rania Rabie, Khalid Mumtaz, Eberhard L. Renner – 23 July 2012 – Cyclosporine A (CSA), but not tacrolimus (TAC), inhibits hepatitis C virus (HCV) replication in vitro. Clinical reports on the efficacy of interferon‐α (IFNα)–based antiviral therapy (AVT) for recurrent HCV after liver transplantation (LT) with CSA and TAC are conflicting. Our aim was to assess whether AVT for recurrent HCV after LT is more effective with CSA or TAC. We performed an electronic database search (1995‐2012) and a manual abstract search (2005‐2012).

Andres F. Carrion, Paul Martin – 23 July 2012 – Watch the interview with the authors

Elizabeth C. Verna, Robert S. Brown – 23 July 2012 – Watch the interview with the authors

Douglas Mogul, Kathleen B. Schwarz – 23 July 2012 – Watch an interview with Dr. Schwarz

Ranjeeta Bahirwani, K. Rajender Reddy – 23 July 2012 – Watch the interview with the authors

Elizabeth C. Verna, Robert S. Brown – 23 July 2012 – Watch the interview with the authors

David C. Mulligan – 23 July 2012

Ranjeeta Bahirwani, K. Rajender Reddy – 23 July 2012 – Watch the interview with the authors

Elizabeth C. Verna, Robert S. Brown – 23 July 2012 – Watch the interview with the authors

Karen M.F. Sze, Glanice K.Y. Chu, Joyce M.F. Lee, Irene O.L. Ng – 23 July 2012 – Random integration of hepatitis B virus (HBV) DNA into the host genome is frequent in human hepatocellular carcinoma (HCC) and this leads to truncation of the HBV DNA, particularly at the C‐terminal end of the HBV X protein (HBx). In this study, we investigated the frequency of this natural C‐terminal truncation of HBx in human HCCs and its functional significance. In 50 HBV‐positive patients with HCC, full‐length HBx was detected in all nontumorous livers.