Heather L. Van Sweringen, Nozomu Sakai, Amit D. Tevar, Justin M. Burns, Michael J. Edwards, Alex B. Lentsch – 29 May 2011 – The process of liver repair and regeneration following hepatic injury is complex and relies on a temporally coordinated integration of several key signaling pathways. Pathways activated by members of the CXC family of chemokines play important roles in the mechanisms of liver repair and regeneration through their effects on hepatocytes. However, little is known about the signaling pathways used by CXC chemokine receptors in hepatocytes.

Nobuhiko Hiraga, Michio Imamura, Hiromi Abe, C. Nelson Hayes, Tomohiko Kono, Mayu Onishi, Masataka Tsuge, Shoichi Takahashi, Hidenori Ochi, Eiji Iwao, Naohiro Kamiya, Ichimaro Yamada, Chise Tateno, Katsutoshi Yoshizato, Hirotaka Matsui, Akinori Kanai, Toshiya Inaba, Shinji Tanaka, Kazuaki Chayama – 29 May 2011 – Telaprevir is a potent inhibitor of hepatitis C virus (HCV) NS3‐4A protease.

Zong‐Gen Peng, Xue‐Fu You, Jian‐Dong Jiang – 29 May 2011

Alessandra Mangia, Alexander J. Thompson, Rosanna Santoro, Valeria Piazzolla, Massimiliano Copetti, Nicola Minerva, Daniela Petruzzellis, Leonardo Mottola, Donato Bacca, John G. McHutchison – 29 May 2011

Ruben Ramirez, Jonathan C. Cohen, Helen H. Hobbs, Jeffrey D. Browning – 29 May 2011

Le‐xing Yu, He‐xin Yan, Wen Yang, Hong‐yang Wang – 29 May 2011

Joanna K. Dowman, Bridget K. Gunson, Darius F. Mirza, Simon R. Bramhall, Mike N. Badminton, Philip N. Newsome, on behalf of the UK Liver Selection and Allocation Working Party – 26 May 2011 – Acute intermittent porphyria (AIP) is an autosomal‐dominant condition resulting from a partial deficiency of the ubiquitously expressed enzyme porphobilinogen deaminase. Although its clinical expression is highly variable, a minority of patients suffer recurrent life‐threatening neurovisceral attacks despite optimal medical therapy.

Luca Fabris, Massimiliano Cadamuro, Lidia Moserle, James Dziura, Xiangyu Cong, Luisa Sambado, Giorgia Nardo, Aurelio Sonzogni, Michele Colledan, Alberto Furlanetto, Nicolò Bassi, Marco Massani, Umberto Cillo, Claudia Mescoli, Stefano Indraccolo, Massimo Rugge, Lajos Okolicsanyi, Mario Strazzabosco – 26 May 2011 – Cholangiocarcinoma (CCA) carries a severe prognosis because of its strong invasiveness and early metastasization. In several patients, otherwise eligible for surgical resection, micrometastasis are already present at the time of surgery.

26 May 2011

Brian J. McMahon, Lisa R. Bulkow, Rosalyn J. Singleton, James Williams, Mary Snowball, Chriss Homan, Alan J. Parkinson – 26 May 2011 – Alaska Native people experience the highest rates of acute and chronic hepatitis B virus (HBV) infection and hepatocellular carcinoma (HCC) in the United States. We examined the effect of a universal newborn immunization with hepatitis B vaccine and mass population screening immunization program initiated in 1984 on rates of HBV and HCC in children 25 years later.