Impact of center volume on outcomes of increased‐risk liver transplants

Deepak K. Ozhathil, You Fu Li, Jillian K. Smith, Jennifer F. Tseng, Reza F. Saidi, Adel Bozorgzadeh, Shimul A. Shah – 20 May 2011 – The use of high‐risk donor livers, which is reflective of the gross national shortage of organs available for transplantation, has gained momentum. Despite the demand, many marginal livers are discarded annually. We evaluated the impact of center volume on survival outcomes associated with liver transplantation using high–donor risk index (DRI) allografts.

Risk factors for long‐term mortality in a large cohort of patients wait‐listed for liver transplantation in Brazil

Samanta T. Basto, Cristiane A. Villela‐Nogueira, Bernardo R. Tura, Henrique Sergio M. Coelho, Joaquim Ribeiro, Eduardo S. M. Fernandes, Alice F. Schmal, Livia Victor, Ronir R. Luiz, Renata M. Perez – 20 May 2011 – Liver donor shortage and long waiting times are observed in many liver transplant programs worldwide. The aim of this study was to evaluate the wait list in a developing country, before and after the introduction of the MELD scoring system. In addition, the MELD score ability to predict mortality in this setting was assessed.

Outcomes of orthotopic liver transplantation for hepatic sarcoidosis: An analysis of the United Network for organ sharing/organ Procurement and Transplantation Network data files for a comparative study with cholestatic liver diseases

Jason M. Vanatta, Kian A. Modanlou, Amanda G. Dean, Nosratollah Nezakatgoo, Luis Campos, Satheesh Nair, James D. Eason – 18 May 2011 – Hepatic sarcoidosis is a rare indication for liver transplantation. Using the United Network for Organ Sharing (UNOS)/Organ Procurement and Transplantation Network (OPTN) database, we evaluated patient and graft survival after orthotopic liver transplantation for sarcoidosis between October 1987 and December 2007.

Volumetry‐based selection of right posterior sector grafts for adult living donor liver transplantation

Bong‐Wan Kim, Weiguang Xu, Hee‐Jung Wang, Yong‐Keun Park, Kwangil Lee, Myung‐Wook Kim – 18 May 2011 – To determine the feasibility of volumetric criteria without anatomic exclusion for the selection of right posterior sector (RPS) grafts for adult‐to‐adult living donor liver transplantation (LDLT), we reviewed and compared our transplant data for RPS grafts and right lobe (RL) grafts.

Use of an upper midline incision for living donor partial hepatectomy: A series of 143 consecutive cases

Kwang‐Woong Lee, Seong Hoon Kim, Sung‐Sik Han, Young‐Kyu Kim, Seong Yeon Cho, Tae You, Sang‐Jae Park – 16 May 2011 – Over a period of 2 years, we used an upper midline incision (UMI) without laparoscopic assistance in 143 consecutive living donor partial hepatectomy (LDPH) procedures, regardless of the graft type or the donor age, sex, body mass index, or body shape. Here we report surgical recommendations based on our experience with the use of UMIs in this context.

Dendritic cell depletion exacerbates acetaminophen hepatotoxicity

Michael K. Connolly, Diego Ayo, Ashim Malhotra, Michael Hackman, Andrea S. Bedrosian, Junaid Ibrahim, Napoleon E. Cieza‐Rubio, Andrew H. Nguyen, Justin R. Henning, Monica Dorvil‐Castro, H. Leon Pachter, George Miller – 13 May 2011 – Acetaminophen (APAP) overdose is one of the most frequent causes of acute liver failure in the United States and is primarily mediated by toxic metabolites that accumulate in the liver upon depletion of glutathione stores.

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