Predictors of cardiovascular events after liver transplantation: A role for pretransplant serum troponin levels

Elizabeth Coss, Kymberly D. S. Watt, Rachel Pedersen, Ross Dierkhising, Julie K. Heimbach, Michael R. Charlton – 20 January 2011 – Cardiovascular complications are major causes of morbidity and mortality after liver transplantation. Identifying candidates at highest risk of postoperative complications is a cornerstone of optimizing outcomes and utility.

Effect of remote ischemic preconditioning on liver ischemia/reperfusion injury using a new mouse model

Mahmoud Abu‐Amara, Shi Yu Yang, Alberto Quaglia, Peter Rowley, Niteen Tapuria, Alexander M. Seifalian, Barry J. Fuller, Brian R. Davidson – 20 January 2011 – Ischemic preconditioning of remote organs (RIPC) reduces liver ischemia/reperfusion (IR) injury in the rabbit and rat. Mice are the only species available with a large number of transgenic strains. This study describes development and validation of a mouse model of hindlimb RIPC that attenuates liver IR injury.

Comparison of radiofrequency ablation and transarterial chemoembolization for hepatocellular carcinoma within the Milan criteria: A propensity score analysis

Chia‐Yang Hsu, Yi‐Hsiang Huang, Yi‐You Chiou, Chien‐Wei Su, Han‐Chieh Lin, Rheun‐Chuan Lee, Jen‐Huey Chiang, Teh‐Ia Huo, Fa‐Yauh Lee, Shou‐Dong Lee – 19 January 2011 – Radiofrequency ablation (RFA) and transarterial chemoembolization (TACE) are used to treat hepatocellular carcinoma (HCC). This study was designed to compare the long‐term survival of HCC patients within the Milan criteria who underwent RFA or TACE. In all, 315 RFA patients and 215 TACE patients with HCC within the Milan criteria were analyzed. Propensity scores were generated to select matched patients.

Reticulon 4B (Nogo‐B) is a novel regulator of hepatic fibrosis

Dahai Zhang, Teruo Utsumi, Hui‐Chun Huang, Lili Gao, Panjamaporn Sangwung, Chuhan Chung, Kazunori Shibao, Kohji Okamoto, Koji Yamaguchi, Roberto J. Groszmann, Levente Jozsef, Zhengrong Hao, William C. Sessa, Yasuko Iwakiri – 19 January 2011 – Nogo‐B, also known as Reticulon 4B, plays important roles in vascular injuries. Its function in the liver is not understood. The aim of this study was to characterize Nogo‐B in liver fibrosis and cirrhosis. Nogo‐B distribution was assessed in normal and cirrhotic human liver sections.

Preoperative estimation of the liver graft weight in adult right lobe living donor liver transplantation using maximal portal vein diameters

Frank Wang, Kuang‐Tse Pan, Sung‐Yu Chu, Kun‐Ming Chan, Hong‐Shiue Chou, Ting‐Jung Wu, Wei‐Chen Lee – 19 January 2011 – An accurate preoperative estimate of the graft weight is vital to avoid small‐for‐size syndrome in the recipient and ensure donor safety after adult living donor liver transplantation (LDLT). Here we describe a simple method for estimating the graft volume (GV) that uses the maximal right portal vein diameter (RPVD) and the maximal left portal vein diameter (LPVD).

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