Carlos M. Rodríguez‐Ortigosa, Jesús M. Banales, Israel Olivas, Iker Uriarte, José J.G. Marín, Fernando J. Corrales, Juan F. Medina, Jesús Prieto – 23 July 2010 – Ursodeoxycholic acid (UDCA) induces bicarbonate‐rich hypercholeresis by incompletely defined mechanisms that involve the stimulation of adenosine triphosphate (ATP) release from cholangiocytes. As nitric oxide (NO) at a low concentration can stimulate a variety of secretory processes, we investigated whether this mediator could be implicated in the choleretic response to UDCA.

Christian D. Fingas, Boris R. A. Blechacz, Rory L. Smoot, Maria E. Guicciardi, Justin Mott, Steve F. Bronk, Nathan W. Werneburg, Alphonse E. Sirica, Gregory J. Gores – 23 July 2010

Kumaravelu Jagavelu, Chittaranjan Routray, Uday Shergill, Steven P. O'Hara, William Faubion, Vijay H. Shah – 23 July 2010 – Angiogenesis defines the growth of new blood vessels from preexisting vascular endothelial networks and corresponds to the wound healing process that is typified by the process of liver fibrosis. Liver fibrosis is also associated with increased endotoxin within the gut lumen and its associated portal circulation.

Eliane Tiemi Miyazaki, Randolfo dos Santos, M. Cristina Miyazaki, Neide M. Domingos, Hellen C. Felicio, Marcia F. Rocha, Paulo C. Arroyo, William J. Duca, Renato F. Silva, Rita C. M. A. Silva – 16 July 2010 – Over the last few decades, informal caregivers of patients with chronic diseases have received more attention, and there is a growing volume of studies demonstrating high rates of burden, stress, and mental disorders in this group of individuals.

James Neuberger, Sue Madden, David Collett – 16 July 2010 – The assessment of outcomes after transplantation is important for several reasons: it provides patients with data so that they can make informed decisions about the benefits of transplantation and the success of the transplant unit; it informs commissioners that resources are allocated properly; and it provides clinicians reassurance that results are acceptable or, if they are not, provides early warning so that problems can be identified, corrections can be instituted early, and all interested parties can be reassured that scarce

Sung Hwan Ki, Oygi Park, Mingquan Zheng, Oriol Morales‐Ibanez, Jay K. Kolls, Ramon Bataller, Bin Gao – 16 July 2010 – Interleukin‐22 (IL‐22), a recently identified member of the IL‐10 family of cytokines that is produced by Th17 and natural killer cells, plays an important role in controlling bacterial infection, homeostasis, and tissue repair. Here, we tested the effect of IL‐22 on alcohol‐induced liver injury in a murine model of chronic‐binge ethanol feeding.

Sumeet K. Asrani, Michael D. Leise, Colin P. West, M. Hassan Murad, Rachel A. Pedersen, Patricia J. Erwin, Jianmin Tian, Russell H. Wiesner, W. Ray Kim – 16 July 2010 – Sirolimus is used in patients with renal insufficiency after liver transplantation (LT) and especially in those with calcineurin inhibitor (CNI)–associated nephrotoxicity.

Gian Luigi Adani, Anna Rossetto, Vittorio Bresadola, Umberto Baccarani – 16 July 2010

Hayato Hikita, Tetsuo Takehara, Satoshi Shimizu, Takahiro Kodama, Minoru Shigekawa, Kyoko Iwase, Atsushi Hosui, Takuya Miyagi, Tomohide Tatsumi, Hisashi Ishida, Wei Li, Tatsuya Kanto, Naoki Hiramatsu, Norio Hayashi – 16 July 2010 – Tumor cells are characterized by uncontrolled proliferation, often driven by activation of oncogenes, and apoptosis resistance.

Claire Francoz, Dominique Prié, Wael AbdelRazek, Richard Moreau, Ameet Mandot, Jacques Belghiti, Dominique Valla, François Durand – 16 July 2010 – Renal function has a significant impact on early mortality in patients with cirrhosis. However, creatinine and creatinine‐based equations are inaccurate markers of renal function in cirrhosis. The aim of this study was to reassess correlations between creatinine‐based equations and measured glomerular filtration rate (GFR) and to investigate the impact of inaccuracies on the Model for End‐Stage Liver Disease (MELD) score.