Erratum: Curcumin inhibits hepatic protein‐tyrosine phosphatase 1B and prevents hypertriglyceridemia and hepatic steatosis in fructose‐fed rats
Jian‐Mei Li, Yu‐Cheng Li, Ling‐Dong Kong, Qing‐Hua Hu – 25 June 2010
Cigarette smoking is not associated with specific histological features or severity of nonalcoholic fatty liver disease
Yusuf Yilmaz, Oya Yonal, Ramazan Kurt, Erol Avsar – 23 June 2010
Carriage of a tumor necrosis factor polymorphism amplifies the cytotoxic T‐lymphocyte antigen 4 attributed risk of primary biliary cirrhosis: Evidence for a gene–gene interaction
Brian D. Juran, Elizabeth J. Atkinson, Joseph J. Larson, Erik M. Schlicht, Xiangdong Liu, E. Jenny Heathcote, Gideon M. Hirschfield, Katherine A. Siminovitch, Konstantinos N. Lazaridis – 23 June 2010 – Common genetic variants significantly influence complex diseases such as primary biliary cirrhosis (PBC). We recently reported an association between PBC and a single nucleotide polymorphism (rs231725) of the immunoreceptor gene cytotoxic T‐lymphocyte antigen 4 (CTLA4).
Theophylline improves steroid sensitivity in acute alcoholic hepatitis
Stuart F. W. Kendrick, Elsbeth Henderson, Jeremy Palmer, David E. J. Jones, Chris P. Day – 23 June 2010 – Corticosteroid therapy has shown some benefit in severe acute alcoholic hepatitis (AAH); however, this is limited by uncertainty in patient selection and variable clinical response. Theophylline has been shown to ameliorate impaired steroid sensitivity in chronic obstructive pulmonary disease by facilitating corticosteroid‐induced silencing of proinflammatory genes.
Reply: Ferritin and Liver Allocation? Impact on Mortality Not Only on the Waiting List But Also After Orthotopic Liver Transplantation Should Be Considered
Darrell H. G. Crawford, Linda M. Fletcher, Katherine A. Stuart – 23 June 2010
To TWEAK, or not to TWEAK: That is the question
David A. Shafritz – 23 June 2010
Comparison of surrogate and direct measurement of insulin resistance in chronic hepatitis C virus infection: Impact of obesity and ethnicity
Khoa D. Lam, Peter Bacchetti, Fahim Abbasi, Claudia E. Ayala, Samuel M. Loeb, Vidhi Shah, Michael J. Wen, Gerald M. Reaven, Jacquelyn J. Maher, Mandana Khalili – 23 June 2010 – Studies using surrogate estimates show high prevalence of insulin resistance in hepatitis C infection. This study prospectively evaluated the correlation between surrogate and directly measured estimates of insulin resistance and the impact of obesity and ethnicity on this relationship.
Deletion of interleukin‐6 in mice with the dominant negative form of transforming growth factor β receptor II improves colitis but exacerbates autoimmune cholangitis
Weici Zhang, Masanobu Tsuda, Guo‐Xiang Yang, Koichi Tsuneyama, Guanghua Rong, William M. Ridgway, Aftab A. Ansari, Richard A. Flavell, Ross L. Coppel, Zhe‐Xiong Lian, M. Eric Gershwin – 23 June 2010 – The role of interleukin‐6 (IL‐6) in autoimmunity attracts attention because of the clinical usage of monoclonal antibodies to IL‐6 receptor (IL‐6R), designed to block IL‐6 pathways.
Use of surveillance for hepatocellular carcinoma among patients with cirrhosis in the United States
Jessica A. Davila, Robert O. Morgan, Peter A. Richardson, Xianglin L. Du, Katherine A. McGlynn, Hashem B. El‐Serag – 23 June 2010 – Surveillance for hepatocellular carcinoma (HCC) in patients with cirrhosis is recommended but may not be performed. The extent and determinants of HCC surveillance are unknown. We conducted a population‐based United States cohort study of patients over 65 years of age to examine use and determinants of prediagnosis surveillance in patients with HCC who were previously diagnosed with cirrhosis.
Reply: Diagnostic Utility of Chromosome 17 and p16 Abnormalities in Fluorescence In Situ Hybridization Tests in Primary Sclerosing Cholangitis
Sanjay Y. Bangarulingam, Einar Björnsson, Felicity Enders, Emily G. Barr Fritcher, Gregory Gores, Kevin C. Halling, Keith D. Lindor – 23 June 2010