Arun Thenappan, Ying Li, Krit Kitisin, Asif Rashid, Kirti Shetty, Lynt Johnson, Lopa Mishra – 26 March 2010 – Adult hepatic progenitor cells are activated during regeneration when hepatocytes and bile duct epithelium are damaged or unable to proliferate. On the basis of its role as a tumor suppressor and in the potential malignant transformation of stem cells in hepatocellular carcinoma, we investigated the role of key transforming growth factor beta (TGF‐β) signaling components, including the Smad3 adaptor protein β2‐Spectrin (β2SP), in liver regeneration.

Carina Riediger, Michael W. Müller, Christoph W. Michalski, Norbert Hüser, Tibor Schuster, Jörg Kleeff, Helmut Friess – 23 March 2010 – The routine use of a T‐tube in reconstruction of the biliary tree during orthotopic liver transplantation (OLT) is controversial. A systematic review of the literature on the use of a T‐tube in reconstruction of the biliary tree was performed. Retrospective studies were only reviewed, whereas prospective randomized studies were included in the meta‐analysis. An analysis of 196 studies revealed that 91 studies investigated the use of a T‐tube in OLT.

Sammy Saab, Douglas R. Hunt, Michael A. Stone, Amy McClune, Myron J. Tong – 23 March 2010 – Antiviral therapy for the treatment of hepatitis C virus (HCV) infection is used before and after liver transplantation. The objective of this study was to determine the most cost‐effective timing for pegylated interferon/ribavirin therapy in patients with advanced liver disease infected with genotype 1 HCV.

Karl‐Heinz Schulz, Sylvia Kroencke – 8 March 2010

Benjamin L. Shneider, Mark S. Roberts, Kyle Soltys – 8 March 2010

Dorry L. Segev, Robert A. Montgomery – 8 March 2010

Pinelopi Manousou, AP Dhillon, Andrew K Burroughs – 8 March 2010

Allan M. Concejero, Chee‐Chien Yong, Chao‐Long Chen, Hung‐I Lu, Chih‐Chi Wang, Shih‐Ho Wang, Yueh‐Wei Liu, Chin‐Hsiang Yang, Yu‐Fan Cheng, Bruno Jawan – 8 March 2010 – Our objectives were to define the incidence and etiology of solitary pulmonary nodules (SPNs) in patients undergoing living donor liver transplantation (LDLT), describe a diagnostic approach to the management of SPNs in LDLT, and define the impact of SPNs on the overall survival of adult LDLT recipients.

Angeline Goh, Mario Scalamogna, Tullia De Feo, Francesca Poli, Paul I. Terasaki – 5 March 2010 – Although human leukocyte antigen (HLA) crossmatching is often thought to be unnecessary for liver transplants (LTs), we provide evidence that for retransplants, it is essential. Sera from 139 retransplant patients who had received livers from deceased donors were retrospectively analyzed with single antigen beads on a Luminex platform for HLA antibodies.

Constantino Fondevila, Amelia J. Hessheimer, Pilar Taurá, Olga Sánchez, David Calatayud, Nicolas de Riva, Javier Muñoz, Jose Fuster, Antoni Rimola, Juan C. García‐Valdecasas – 5 March 2010 – Understanding the pathogenesis of small‐for‐size (SFS) syndrome is critical to expanding the applicability of partial liver transplantation. We aimed to characterize its acute presentation and association with alterations in hepatic hemodynamics, microstructure, and regeneration in a porcine model. Eighteen SFS liver transplants were performed. Donors underwent 70% hepatectomy.