Characterization of the middle hepatic artery and its relevance to living donor liver transplantation
Shaofa Wang, Xiaoshun He, Ziping Li, Zhenpeng Peng, Nga Lei Tam, Canhui Sun, Anbin Hu, Jiefu Huang – 13 April 2010 – In comparison with the left and right hepatic arteries, there is a relative lack of information on the middle hepatic artery (MHA). In this study, data obtained by multidetector computed tomography from 145 patients were studied to evaluate anatomical variations of the MHA, a hilar artery that primarily supplies hepatic segment 4. An MHA was present in 103 (71%) of the subjects.
Massive diaphragmatic herniation following orthotopic liver transplantation in an adult
Doris Wagner, Florian Iberer, Michael Sereinigg, Daniela Kniepeiss, Peter Kornprat, Astrid Fahrleitner‐Pammer, Philipp Stiegler, Karlheinz Tscheliessnigg – 6 April 2010
Patatin‐like phospholipase domain containing 3: A case in point linking genetic susceptibility for alcoholic and nonalcoholic liver disease
Devanshi Seth, Ann K. Daly, Paul S. Haber, Christopher P. Day – 29 March 2010
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Elisa Fabbrini, Shelby Sullivan, Samuel Klein – 29 March 2010
Antagonizing MicroRNA‐122 and treatment of hepatitis C virus infection
Sébastien Pfeffer, Thomas F. Baumert – 29 March 2010
Paired donor interchange to avoid ABO‐incompatible living donor liver transplantation
See Ching Chan, Chung Mau Lo, Boon Hun Yong, Wilson J. C. Tsui, Kelvin K. C. Ng, Sheung Tat Fan – 29 March 2010 – We report an emergency paired donor interchange living donor liver transplant performed on January 13, 2009. The 4 operations (2 liver transplants) were performed simultaneously. The aim was to avoid 2 ABO‐incompatible liver transplants. One recipient in acute liver failure underwent transplantation in a high‐urgency situation.
Role of transforming growth factor β signaling and expansion of progenitor cells in regenerating liver
Arun Thenappan, Ying Li, Krit Kitisin, Asif Rashid, Kirti Shetty, Lynt Johnson, Lopa Mishra – 26 March 2010 – Adult hepatic progenitor cells are activated during regeneration when hepatocytes and bile duct epithelium are damaged or unable to proliferate. On the basis of its role as a tumor suppressor and in the potential malignant transformation of stem cells in hepatocellular carcinoma, we investigated the role of key transforming growth factor beta (TGF‐β) signaling components, including the Smad3 adaptor protein β2‐Spectrin (β2SP), in liver regeneration.
Disruption of the growth hormone—Signal transducer and activator of transcription 5—Insulinlike growth factor 1 axis severely aggravates liver fibrosis in a mouse model of cholestasis
Leander Blaas, Jan‐Wilhelm Kornfeld, Daniel Schramek, Monica Musteanu, Gernot Zollner, Judith Gumhold, Franziska van Zijl, Doris Schneller, Harald Esterbauer, Gerda Egger, Markus Mair, Lukas Kenner, Wolfgang Mikulits, Robert Eferl, Richard Moriggl, Josef Penninger, Michael Trauner, Emilio Casanova – 26 March 2010 – Growth hormone (GH) resistance and low serum levels of insulinlike growth factor 1 (IGF‐1) are common features in human liver fibrosis and cirrhosis.
Biliary physiology and disease: Reflections of a physician‐scientist
Gustav Paumgartner – 26 March 2010 – A review is presented of Gustav Paumgartner's five decades of research and practice in hepatology focusing on biliary physiology and disease. It begins with studies of the excretory function of the liver including hepatic uptake of indocyanine green, bilirubin, and bile acids. The implications of these studies for diagnosis and understanding of liver diseases are pointed out. From there, the path of scientific research leads to investigations of hepatobiliary bile acid transport and the major mechanisms of bile formation.