Eric Vibert, Jean‐Charles Duclos‐Vallée, Maria‐Rosa Ghigna, Emir Hoti, Chady Salloum, Catherine Guettier, Denis Castaing, Didier Samuel, René Adam – 4 November 2010 – Liver transplantation (LT) has become an accepted therapy for end‐stage liver disease in human immunodeficiency virus–positive (HIV+) patients, but the specific results of LT for hepatocellular carcinoma (HCC) are unknown. Between 2003 and 2008, 21 HIV+ patients and 65 HIV− patients with HCC were listed for LT at a single institution. Patient characteristics and pathological features were analyzed.

Marco Antonio Montes‐Cano, José Raúl García‐Lozano, Cristina Abad‐Molina, Fuensanta Torrecillas, Almudena Torres, Luis Felipe Lopez‐Cortes, Antonio Núñez‐Roldán, María Francisca González‐Escribano – 4 November 2010

Salvatore Petta, Marco Amato, Daniela Cabibi, Calogero Cammà, Vito Di Marco, Carla Giordano, Aldo Galluzzo, Antonio Craxì – 29 October 2010 – Metabolic factors have been associated with liver damage in patients with genotype 1 chronic hepatitis C (G1 CHC). We tested visceral adiposity index (VAI), a new marker of adipose dysfunction in G1 CHC, patients to assess its association with host and viral factors and its link to both histological findings and sustained virological response (SVR).

Dawn McDowell Torres, Stephen A. Harrison – 29 October 2010

Martin Rössle, Daniel Grandt – 29 October 2010

Lei Wan, Chang‐Hai Tsai, Chin‐Moo Hsu, Chin‐Chang Huang, Chih‐Chao Yang, Chiu‐Chu Liao, Chin‐Ching Wu, Yu‐An Hsu, Cheng‐Chun Lee, Su‐Ching Liu, Wei‐De Lin, Fuu‐Jen Tsai – 29 October 2010 – Wilson disease is a copper metabolism disorder caused by mutations in ATP7B, a copper‐transporting adenosine triphosphatase. A molecular diagnosis was performed on 135 patients with Wilson disease in Taiwan.

Ian Guest, Zoran Ilic, Stewart Sell – 29 October 2010 – The age dependence of the oval cell response and bile duct carcinomas of male F344 rats exposed to a cyclic choline deficiency‐ethionine (CDE) diet (2 weeks on, 1 week off) supports the concept of loss of potential of liver stem cells to form cancers with aging. Livers of rats exposed at 3 weeks of age demonstrated a robust and widespread oval cell proliferation followed by cholangiofibrosis and bile duct metaplasia with extensive mucinous cysts throughout all lobes, and induction of cholangiocarcinomas (CCAs) in seven of eight rats.

Joanna D. Stewart, Rita Horvath, Enrico Baruffini, Iliana Ferrero, Stefanie Bulst, Paul B. Watkins, Robert J. Fontana, Christopher P. Day, Patrick F. Chinnery – 29 October 2010 – Sodium valproate (VPA) is widely used throughout the world to treat epilepsy, migraine, chronic headache, bipolar disorder, and as adjuvant chemotherapy. VPA toxicity is an uncommon but potentially fatal cause of idiosyncratic liver injury. Rare mutations in POLG, which codes for the mitochondrial DNA polymerase γ (polγ), cause Alpers‐Huttenlocher syndrome (AHS).

Jayant A. Talwalkar – 29 October 2010

Fumitaka Suzuki, Yoshiyuki Suzuki, Norio Akuta, Hitomi Sezaki, Miharu Hirakawa, Yusuke Kawamura, Tetsuya Hosaka, Masahiro Kobayashi, Satoshi Saito, Yasuji Arase, Kenji Ikeda, Mariko Kobayashi, Kazuaki Chayama, Naoyuki Kamatani, Yusuke Nakamura, Yuzo Miyakawa, Hiromitsu Kumada – 29 October 2010 – Polymorphisms of the inosine triphosphatase (ITPA) gene influence anemia during pegylated interferon (PEG‐IFN) and ribavirin (RBV) therapy, but their effects during triple therapy with PEG‐IFN, RBV, and telaprevir are not known.