Necrosis versus apoptosis in acetaminophen‐induced hepatotoxicity
Klaus Schulze‐ Osthoff, Heike Bantel – 6 October 2010
Working with a gold‐plated standard
Terry Therneau – 6 October 2010
Meeting vaccination quality measures for hepatitis A and B virus in patients with chronic hepatitis C infection
Jennifer R. Kramer, Christine Y. Hachem, Fasiha Kanwal, Minghua Mei, Hashem B. El‐Serag – 6 October 2010 – Coinfection with hepatitis A virus (HAV) or hepatitis B virus (HBV) in patients with chronic hepatitis C virus (HCV) is associated with increased morbidity and mortality. The Center for Medicare and Medicaid Services has identified HAV and HBV vaccination as a priority area for quality measurement in HCV. It is unclear to what extent patients with HCV meet these recommendations.
Proceed with caution: Peginterferon alpha‐2a versus peginterferon alfa‐2b in chronic hepatitis C. A systematic review of randomized trials
David Kershenobich, Linda Muñoz, René Malé, Jesús Gaytan, Francisco Sánchez – 6 October 2010
Is achievement of sustained virologic response an independent predictor or a cofactor for the development of esophageal varices?
Li‐Ping Ye, Xin‐Li Mao – 6 October 2010
Apoptotic cells attenuate fulminant hepatitis by priming Kupffer cells to produce interleukin‐10 through membrane‐bound TGF‐β
Minggang Zhang, Sheng Xu, Yanmei Han, Xuetao Cao – 6 October 2010 – The liver, a unique tolerogenic organ, is regarded as the site to trap and destroy aging erythrocytes and activated T cells. However, to date, the mechanisms for why the liver is tolerogenic and whether liver Kupffer cells (KC) are critical phagocytes for apoptotic cells (AC) contributing to the liver immunosuppression remain unclear. Here we report that KC is the main phagocyte for AC in the liver.
Erratum: Patatin‐like phospholipase domain‐containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease
Weiqin Chen, Benny Chang, Lan Li, Lawrence Chan – 5 October 2010
Drug‐induced postinfantile giant cell hepatitis
Ricardo Moreno‐Otero, María Trapero‐Marugán, Luisa García‐Buey, Asunción García‐Sancchez – 1 October 2010
Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians
Felix Stickel, Stephan Buch, Katharina Lau, Henriette Meyer zu Schwabedissen, Thomas Berg, Monika Ridinger, Marcella Rietschel, Clemens Schafmayer, Felix Braun, Holger Hinrichsen, Rainer Günther, Alexander Arlt, Marcus Seeger, Sebastian Müller, Helmut Karl Seitz, Michael Soyka, Markus Lerch, Frank Lammert, Christoph Sarrazin, Ralf Kubitz, Dieter Häussinger, Claus Hellerbrand, Dieter Bröring, Stefan Schreiber, Falk Kiefer, Rainer Spanagel, Karl Mann, Christian Datz, Michael Krawczak, Norbert Wodarz, Henry Völzke, Jochen Hampe – 30 September 2010 – A recent genome‐wide study revealed an assoc
Noninvasive assessment of liver fibrosis
Stella M. Martínez, Gonzalo Crespo, Miquel Navasa, Xavier Forns – 30 September 2010 – Liver biopsy has long been an important tool for assessing the degree of liver fibrosis. Information on the presence and degree of liver fibrosis is useful before making therapeutic decisions or predicting disease outcomes. The need to stage liver fibrosis, however, should decrease as treatment options become more successful (as has occurred with viral hepatitis).