Ismail Ben Mosbah, Joan Roselló‐Catafau, Izabel Alfany‐Fernandez, Antoni Rimola, Pera Puig Parellada, Maria Teresa Mitjavila, Antonin Lojek, Hassen Ben Abdennebi, Olivier Boillot, Juan Rodés, Carmen Peralta – 26 January 2010 – Here we examine the effect of adding carvedilol (CVD) to University of Wisconsin (UW) solution on the preservation of steatotic and nonsteatotic livers during cold ischemia and after normothermic reperfusion. We used an isolated perfused rat liver model. The following protocols were evaluated. Protocol 1 concerned the effect of CVD after cold ischemia.

William Gelson, Matthew Hoare, Sarah Vowler, Arun Shankar, Paul Gibbs, Arne N. Akbar, Graeme J. M. Alexander – 25 January 2010 – Immune senescence is the normal process whereby the human immune system ages, but becomes less effective. We investigated whether liver transplant recipients have features of immune senescence.

Tao Sun, Nan Zhao, Xiu‐lan Zhao, Qiang Gu, Shi‐wu Zhang, Na Che, Xing‐hui Wang, Jing Du, Yi‐xin Liu, Bao‐cun Sun – 25 January 2010 – The up‐regulation and nuclear relocation of epithelial‐mesenchymal transition (EMT) regulator Twist1 have been implicated in the tumor invasion and metastasis of human hepatocellular carcinoma (HCC). The term vasculogenic mimicry (VM) refers to the unique capability of aggressive tumor cells to mimic the pattern of embryonic vasculogenic networks. However, the relationship between Twist1 and VM formation is not clear.

Lise L. Gluud, Kurt Christensen, Erik Christensen, Aleksander Krag – 25 January 2010 – Vasoconstrictor drugs may improve renal function in hepatorenal syndrome (HRS), but the effect on mortality has not been established. We therefore performed a systematic review of randomized trials on vasoconstrictor drugs for type 1 or type 2 HRS. Mortality was the primary outcome measure. Eligible trials were identified through electronic and manual searches. Intention‐to‐treat random effects meta‐analyses were performed.

Philip N. Newsome – 25 January 2010

Leon Adams – 25 January 2010

Yu‐Xiong Feng, Jiang‐Sha Zhao, Jing‐Jing Li, Tao Wang, Shu‐Qun Cheng, Yunfei Yuan, Fudi Wang, Xiao‐Fan Wang, Dong Xie – 25 January 2010 – Eph/Ephrin family, one of the largest receptor tyrosine kinase families, has been extensively studied in morphogenesis and neural development. Recently, growing attention has been paid to its role in the initiation and progression of various cancers. However, the role of Eph/Ephrins in hepatocellular carcinoma (HCC) has been rarely investigated.

David W. Hutton, Samuel K. So, Margaret L. Brandeau – 25 January 2010 – Liver disease and liver cancer associated with childhood‐acquired chronic hepatitis B are leading causes of death among adults in China. Despite expanded newborn hepatitis B vaccination programs, approximately 20% of children under age 5 years and 40% of children aged 5 to 19 years remain unprotected from hepatitis B. Although immunizing them will be beneficial, no studies have examined the cost‐effectiveness of hepatitis B catch‐up vaccination in an endemic country like China.

J. Wallis Marsh, Carl Schmidt – 25 January 2010

Paula M. Buchanan, Nino Dzebisashvili, Krista L. Lentine, David A. Axelrod, Mark A. Schnitzler, Paolo R. Salvalaggio – 25 January 2010