In‐hospital mortality in adult recipients of living donor liver transplantation: Experience of 576 consecutive cases at a single center

Toshimi Kaido, Hiroto Egawa, Hiroaki Tsuji, Eishi Ashihara, Taira Maekawa, Shinji Uemoto – 28 October 2009 – Adult living donor liver transplantation (LDLT) was developed against the background of a scarcity of deceased donors and has a number of disadvantages leading to in‐hospital mortality, such as marginal donors and grafts and recipients suffering from severe conditions. We have thus developed surgical and medical innovations to overcome these disadvantages. The present study analyzes the causes of death and factors affecting in‐hospital mortality in adult recipients of LDLT.

Effects of obesity, diabetes, and prior abdominal surgery on resource utilization in liver transplantation: A single‐center study

Satheesh Nair, Jason M. Vanatta, Jihad Arteh, James D. Eason – 28 October 2009 – Obesity, diabetes, and prior abdominal surgery are generally considered to increase the risk of liver transplantation. The aim of the present study was to define the effects of these factors on the immediate outcome after transplantation. Two hundred twenty‐one consecutive liver transplants were analyzed. Twenty‐eight patients were excluded.

Characteristics and management of splenic artery aneurysms in adult living donor liver transplant recipients

Deok‐Bog Moon, Sung‐Gyu Lee, Shin Hwang, Ki‐Hun Kim, Chul‐Soo Ahn, Tae‐Yong Ha, Gi‐Won Song, Dong‐Hwan Jung, Gi‐Young Ko, Kyu‐Bo Sung – 28 October 2009 – Splenic artery aneurysms (SAAs), occurring in 7% to 17% of patients with cirrhosis, often result in catastrophic rupture after liver transplantation. We had experienced 3 cases of ruptured SAAs after adult living donor liver transplantation (LDLT), and we then performed this study to find risk factors for coexisting SAAs in liver transplant candidates with cirrhosis and to propose ideal approaches for them.

Donor and recipient selection leads to good patient and graft outcomes for right lobe split transplantation versus whole graft liver transplantation in adult recipients

Charbel Sandroussi, Michael Crawford, David S. Lockwood, Patrick Tang, James P. Gallagher, Henry Pleass, Simone I. Strasser, Nicholas A. Shackel, Geoffrey W. McCaughan, Deborah J. Verran – 28 October 2009 – The outcomes of right lobe split (RLS) liver transplantation are variable in adult recipients. This report is an analysis of outcomes of our initial 5‐year experience with the right lobe trisegment split graft.

Intimal dissection of the hepatic artery following transarterial embolization for hepatocellular carcinoma: An intraoperative problem in adult living donor liver transplantation

Tsan‐Shiun Lin, Yuan‐Cheng Chiang, Chao‐Long Chen, Allan M. Concejero, Yu‐Fan Cheng, Chih‐Chi Wang, Shih‐Ho Wang, Yueh‐Wei Liu, Chin‐Hsiang Yang, Chee‐Chien Yong – 28 October 2009 – The objective of this study was to describe the relationship between intimal dissection (ID) in the recipient hepatic artery (HA) and transarterial embolization (TAE) and highlight the reconstructive methods for the different types of ID encountered in living donor liver transplantation (LDLT). Fifty‐four patients with hepatocellular carcinoma underwent LDLT.

Outcome of acute liver failure in the elderly

Frank V. Schiødt, Raymond T. Chung, Michael L. Schilsky, J. Eileen Hay, Erik Christensen, William M. Lee – 28 October 2009 – Older age is considered a poor prognostic factor in acute liver failure (ALF) and may still be considered a relative contraindication for liver transplantation for ALF. We aimed to evaluate the impact of older age, defined as age ≥ 60 years, on outcomes in patients with ALF. One thousand one hundred twenty‐six consecutive prospective patients from the US Acute Liver Failure Study Group registry were studied. The median age was 38 years (range, 15–81 years).

Financial, vocational, and interpersonal impact of living liver donation

Susan Holtzman, Lesley Adcock, Derek A. Dubay, George Therapondos, Arash Kashfi, Sarah Greenwood, Eberhard L. Renner, David R. Grant, Gary A. Levy, Susan E. Abbey – 28 October 2009 – The ability to inform prospective donors of the psychosocial risks of living liver donation is currently limited by the scant empirical literature. The present study was designed to examine donor perceptions of the impact of donation on financial, vocational, and interpersonal life domains and identify demographic and clinical factors related to longer recovery times and greater life interference.

Recurrence of hepatocellular carcinoma and hepatitis B reinfection in hepatitis B surface antigen–positive patients after liver transplantation

Sammy Saab, Melina Yeganeh, Kelvin Nguyen, Francisco Durazo, Steven Han, Hasan Yersiz, Douglas G. Farmer, Leonard I. Goldstein, Myron J. Tong, Ronald W. Busuttil – 28 October 2009 – Hepatitis B virus (HBV) reinfection and recurrence of hepatocellular carcinoma (HCC) after orthotopic liver transplantation (OLT) are associated with increased graft failure and reduced patient survival. We evaluated the effects of both HCC recurrence and HBV reinfection on the long‐term survival of these patients after OLT.

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