The therapeutic potential of human umbilical mesenchymal stem cells from Wharton's jelly in the treatment of rat liver fibrosis

Pei‐Chun Tsai, Tz‐Win Fu, Yi‐Ming Arthur Chen, Tsui‐Ling Ko, Tien‐Hua Chen, Yang‐Hsin Shih, Shih‐Chieh Hung, Yu‐Show Fu – 27 April 2009 – We investigated the effect of human umbilical mesenchymal stem cells (HUMSCs) from Wharton's jelly on carbon tetrachloride (CCl4)–induced liver fibrosis in rats. Rats were treated with CCl4 for 4 weeks, and this was followed by a direct injection of HUMSCs into their livers.

Hepatitis B: The virus and disease

T. Jake Liang – 27 April 2009 – Hepatitis B virus (HBV) infects more than 300 million people worldwide and is a common cause of liver disease and liver cancer. HBV, a member of the Hepadnaviridae family, is a small DNA virus with unusual features similar to retroviruses. HBV replicates through an RNA intermediate and can integrate into the host genome. The unique features of the HBV replication cycle confer a distinct ability of the virus to persist in infected cells.

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