Ashwin N. Ananthakrishnan, Emily L. McGinley, Kia Saeian – 28 August 2008 – Acute liver failure (ALF) often requires multidisciplinary support. Higher hospital volumes have been associated with better outcomes for surgical procedures, but whether such a relationship exists for ALF has not been explored previously. In this study, our aim was to examine if hospital volume affects mortality from ALF.
Nizar N. Zein, Ibrahim A. Hanouneh – 28 August 2008
Giancarlo Spinzi, Natalia Terreni, Giovanna Mandelli, Silvia Paggi – 28 August 2008
Ahmed Zaky, Ernesto A. Pretto, Steven A. Earle, Emanuele Piraccini, Jennifer E. Zuccarelli, Kristopher L. Arheart, Kenneth G. Proctor – 28 August 2008 – We tested the hypothesis that hepatosplanchnic and systemic hemodynamics are improved with equi‐effective doses of dopamine (DA) versus norepinephrine (NE) in a brain‐dead swine model. Pigs (n = 18) were anesthetized and ventilated. Brain death was induced by epidural balloon inflation, hypoventilation, and hypoxia. After 30 minutes, mechanical ventilation was restored without anesthesia.
7 August 2008
Hartmut Jaeschke – 4 August 2008
Valentina Medici, Lorenzo Rossaro, Jacob A. Wegelin, Amit Kamboj, Junko Nakai, Kelli Fisher, Frederick J. Meyers – 30 July 2008 – Patients with chronic liver disease are referred late to hospice or never referred. There are several barriers to timely referral. First, liver transplantation (LT) and hospice care have always been perceived as mutually exclusive. Yet the criteria for hospice referral and for LT are more similar than different (for example, advanced liver disease and imminent death). Second, physicians, patients, and families have not had a reliable metric to guide referral.
Mitchell L. Shiffman, Don C. Rockey – 30 July 2008 – Liver transplantation has evolved into a successful option for patients with end‐stage liver disease. Transplant hepatologists are involved in the management of patients with end‐stage liver disease both before and after liver transplantation. The goals of this study were to evaluate the roles that transplant hepatologists play at liver transplantation programs in the United States and the demand for and institutional support provided for these physicians.
James D. Perkins – 30 July 2008
Rajasekhar Tanikella, George M. Philips, Dorothy K. Faulk, Steven M. Kawut, Michael B. Fallon – 30 July 2008 – Hepatopulmonary syndrome (HPS) results when chronic liver disease or portal hypertension causes intrapulmonary microvascular dilatation with hypoxemia. In experimental HPS, tumor necrosis factor alpha (TNF‐α) overproduction contributes to vasodilatation, which is improved by pentoxifylline, a TNF‐α inhibitor. The effectiveness of pentoxifylline in humans is unknown.