Constantino Fondevila, Xiu‐Da Shen, Seiichiro Tsuchihashi, Yoichiro Uchida, Maria Cecilia Freitas, Bibo Ke, Ronald W. Busuttil, Jerzy W. Kupiec‐Weglinski – 30 July 2008 – Activation of the complement cascade represents an important event during ischemia/reperfusion injury (IRI). This work was designed to investigate the role of the membrane attack complex (MAC; C5b‐9) in the pathogenesis of hepatic IRI. Livers from B&W/Stahl/rC6(+) and C6(−) rats were harvested, stored for 24 hours at 4°C, and then transplanted [orthotopic liver transplantation (OLT)] to syngeneic recipients.

Mariagrazia Tateo, Mylène Sebagh, Marie‐Pierre Bralet, Elina Teicher, Daniel Azoulay, Vincent Mallet, Stanislas Pol, Denis Castaing, Didier Samuel, Jean‐Charles Duclos‐Vallée – 30 July 2008 – Nodular regenerative hyperplasia is one of the causes of noncirrhotic portal hypertension and has recently been described in human immunodeficiency virus–infected patients, and the potential role of a prothrombotic state and hepatotoxic antiretroviral medication has been suggested. Moreover, it is now established that liver transplantation is feasible in HIV‐infected patients.

Kensuke Miyazaki, Mitsuhisa Takatsuki, Susumu Eguchi, Masaaki Hidaka, Hirotaka Tokai, Koji Hamasaki, Yoshitsugu Tajima, Takashi Kanematsu – 30 July 2008

P. V. Suneetha, Ingmar Mederacke, Albert Heim, Murat Bastürk, Markus Cornberg, Christian P. Strassburg, Michael P. Manns, Heiner Wedemeyer – 30 July 2008

Chen Hao, Mao Anwei, Chen Bing, Shen Baiyong, Zhang Weixia, Shen Chuan, Chen Erzhen, Deng Xiaxing, Qiu Weihua, Yang Weiping, Peng Chenghong, Li Hongwei – 30 July 2008 – Mycophenolate mofetil (MMF) is a very powerful immunosuppressive drug used in preventing acute rejection in liver transplantation. However, MMF has some serious side effects, including hematologic and gastrointestinal disorders. This study was designed to investigate the relationship between the clinical events and the pharmacokinetics of mycophenolic acid (MPA) in Chinese liver transplant recipients.

Sandy Feng – 30 July 2008

Sasan Roayaie, Myron E. Schwartz – 30 July 2008

Natasha S. Becker, Neal R. Barshes, Thomas A. Aloia, Tuan Nguyen, Javier Rojo, Joel A. Rodriguez, Christine A. O'Mahony, Saul J. Karpen, John A. Goss – 30 July 2008 – Two strategies to increase the donor allograft pool for pediatric orthotopic liver transplantation (OLT) are deceased donor segmental liver transplantation (DDSLT) and living donor liver transplantation (LDLT). The purpose of this study is to evaluate outcomes after use of these alternative allograft types.

Nikolaos Arkadopoulos, Demetrios Vlahakos, Georgia Kostopanagiotou, Dimitrios Panagopoulos, Eleni Karvouni, Christina Routsi, Konstantinos Kalimeris, Ioanna Andreadou, Evangelia Kouskouni, Vassilios Smyrniotis – 30 July 2008 – Oxidative mechanisms have been implicated in the pathogenesis of brain edema in acute liver failure (ALF). The aim of this study was to test the hypothesis that inhibition of iron‐catalyzed oxidative reactions through iron chelation using deferoxamine could attenuate brain edema in a swine model of ischemic ALF.

Christian Toso, James Trotter, Alice Wei, David L. Bigam, Shimul Shah, Joshua Lancaster, David R. Grant, Paul D. Greig, A. M. James Shapiro, Norman M. Kneteman – 30 July 2008 – Criteria for the selection of candidates for liver transplantation in the presence of hepatocellular carcinoma (HCC) should accurately predict posttransplant recurrence while not excluding excessive numbers of patients from candidacy. Existing criteria are challenged by the limited accuracy of radiological assessment. The total tumor volume (TTV) was calculated by the addition of the volume of each individual tumor.