Monitoring peripheral blood CD4+ adenosine triphosphate activity in a liver transplant cohort: Insight into the interplay between hepatitis C virus infection and cellular immunity

Michel Mendler, Hansen Kwok, Edson Franco, Pedro Baron, Jill Weissman, Okechukwu Ojogho – 28 August 2008 – Peripheral blood CD4+ adenosine triphosphate [ATP (ng/mL)] release [ImmuKnow Immune Cell Function Assay (ATP)] correlates to immunoreactivity. We hypothesized that ATP levels could provide insight into hepatitis C virus (HCV) infection and recurrent liver disease in liver transplantation (LT). We studied our center's LT cohort, in which ATP levels had been measured off protocol from February 2005 through July 2006.

Outcomes of living donor liver transplantation for acute liver failure: The adult‐to‐adult living donor liver transplantation cohort study

Jeffrey Campsen, Andres T. Blei, Jean C. Emond, James E. Everhart, Chris E. Freise, Anna S. Lok, Sammy Saab, Karen A. Wisniewski, James F. Trotter, Adult‐to‐Adult Living Donor Liver Transplantation Cohort Study Group – 28 August 2008 – For acute liver failure (ALF), living donor liver transplantation (LDLT) may reduce waiting time and provide better timing compared to deceased donor liver transplantation (DDLT).

The effects of desflurane and propofol‐remifentanil on postoperative hepatic and renal functions after right hepatectomy in liver donors

Justin Sang Ko, Mi Sook Gwak, Soo Joo Choi, Gaab Soo Kim, Jie Ae Kim, Mikyung Yang, Sangmin Maria Lee, Hyun Sung Cho, In Sun Chung, Myung Hee Kim – 30 July 2008 – Various volatile anesthetics have been used in hepatectomy in living donors, and their effects on major organs have been extensively evaluated. However, the impact of total intravenous anesthesia (TIVA) on postoperative liver and renal functions after large liver resections has been less extensively investigated than that of volatile agents.

Donor safety and remnant liver volume in living donor liver transplantation

C. Burcin Taner, Murat Dayangac, Baris Akin, Deniz Balci, Suleyman Uraz, Cihan Duran, Refik Killi, Omer Ayanoglu, Yildiray Yuzer, Yaman Tokat – 30 July 2008 – Living donor liver transplantation is now a common practice in countries in which the availability of cadaveric organs is limited. The preoperative preparation, intraoperative surgical technique, and postoperative care of donors and recipients have evolved in recent years.

Bile leak following living donor liver transplantation: Clinical efficacy of percutaneous transhepatic treatment

Jin Hyoung Kim, Gi‐Young Ko, Kyu‐Bo Sung, Hyun‐Ki Yoon, Dong Il Gwon, Kyung Rae Kim, Sung‐Gyu Lee – 30 July 2008 – Percutaneous transhepatic treatment may be effective in patients with bile leaks after living donor liver transplantation (LDLT). We therefore evaluated the clinical efficacy of percutaneous transhepatic treatment for biliary leaks in adult‐to‐adult LDLT recipients. Twenty‐three LDLT recipients underwent percutaneous transhepatic treatment to manage bile leaks. The treatment included percutaneous transhepatic biliary drainage (PTBD) and drainage of perihepatic biloma.

Efficacy and safety of valganciclovir in liver‐transplanted children infected with Epstein‐Barr virus

Loreto Hierro, Ruth Díez‐Dorado, Carmen Díaz, Angela De la Vega, Esteban Frauca, Carmen Camarena, Gema Muñoz‐Bartolo, Ana González de Zárate, Manuel López Santamaría, Paloma Jara – 30 July 2008 – Epstein‐Barr virus (EBV) infection after liver transplantation (LT) is associated with increased risk of posttransplant lymphoproliferative disorder (PTLD). Lowering immunosuppression is the current method to prevent PTLD in LT children with a high viral load. The aim of this study was to assess the efficacy and safety of valganciclovir (VGCV) in children with EBV infection after LT.

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