Tanya Newnham, Winita Hardikar, Katrina Allen, R. Mark Wellard, Charles Hamilton, Peter Angus, Robert Jones, Avihu Boneh – 27 December 2007 – We report successful liver transplantation in a young adult with argininosuccinic aciduria but without cirrhosis. Plasma amino acid profile normalized and brain magnetic resonance spectroscopy indicated improved metabolism after transplantation. The general well‐being of the patient and his quality of life improved.

Raymond T. Chung, Michael Gale, Stephen J. Polyak, Stanley M. Lemon, T. Jake Liang, Jay H. Hoofnagle – 27 December 2007

Savino Bruno, Patrick Maisonneuve, Mario U. Mondelli – 27 December 2007

Oren K. Fix – 27 December 2007

27 December 2007

Kenneth Washburn – 27 December 2007

Mike A. Leonis, William F. Balistreri – 27 December 2007

Jayant A. Talwalkar, Meng Yin, Jeff L. Fidler, Schuyler O. Sanderson, Patrick S. Kamath, Richard L. Ehman – 27 December 2007 – Chronic liver disease and cirrhosis remains a major public health problem worldwide. While the majority of complications from chronic liver disease result from progressive hepatic fibrosis, the available diagnostic tests used in clinical practice are not sensitive or specific enough to detect occult liver injury at early or intermediate stages.

Ye H. Oo, Tracey Dudley, Peter Nightingale, Geoffrey Haydon, David Mutimer – 27 December 2007 – Hepatitis C virus (HCV)‐induced cirrhosis is the most common indication for liver transplantation (LT). However, graft reinfection is nearly universal. The choice of immunosuppression, including the calcineurin inhibitor (CNI), may have some effect on severity of recurrence and graft survival. In addition, HCV recurrence may have some impact on metabolism of immunosuppressive drugs.

Iman Bajjoka, Lama Hsaiky, Kimberly Brown, Marwan Abouljoud – 27 December 2007 – Early renal dysfunction following liver transplantation is associated with increased morbidity and mortality. To evaluate the impact of delayed initiation of calcineurin inhibitor on renal function, we conducted a retrospective study comparing 118 liver transplant recipients who received rabbit anti‐thymocyte globulin and delayed initiation of calcineurin inhibitor with 80 liver transplant recipients who received no antibody and early initiation of calcineurin inhibitor (control group).