Liver transplantation in patients over 60 and 65 years: An evaluation of long‐term outcomes and survival

Timothy J.S. Cross, Charalambos G. Antoniades, Paolo Muiesan, Thawab Al‐Chalabi, Varuna Aluvihare, Kosh Agarwal, Bernard C. Portmann, Mohammed Rela, Nigel D. Heaton, John G. O'Grady, Michael A. Heneghan – 27 September 2007 – With increased demand for liver transplantation (LT), outcomes of older recipients have been subjected to greater scrutiny, as previous studies have demonstrated poorer survival outcomes.

Liver transplantation using suboptimal grafts: Impact of donor harvesting technique

Francesco D'Amico, Alessandro Vitale, Enrico Gringeri, Michele Valmasoni, Amedeo Carraro, Alberto Brolese, Giacomo Zanus, Patrizia Boccagni, Davide Francesco D'Amico, Umberto Cillo – 27 September 2007 – In recent years, an increasing number of suboptimal grafts has been used to reduce the gap between the supply and demand of organs for liver transplantation (LT). In this randomized prospective study, we tested the impact of donor harvesting technique on the posttransplantation outcome of suboptimal donor livers.

An assessment of interactions between hepatitis C virus and herpesvirus reactivation in liver transplant recipients using molecular surveillance

Atul Humar, Kenneth Washburn, Richard Freeman, Carlos V. Paya, Houria Mouas, Emma Alecock, Raymund R. Razonable, PV16000 Study Group – 27 September 2007 – Hepatitis C virus (HCV) has been proposed to have immunomodulatory effects in transplant recipients and may promote herpesvirus reactivation. To assess this, we compared the incidence of herpesvirus reactivation in HCV‐positive and HCV‐negative liver transplant recipients.

Human leukocyte antigen and adult living‐donor liver transplantation outcomes: An analysis of the organ procurement and transplantation network database

S. Simona Jakab, Victor J. Navarro, Beth W. Colombe, Constantine Daskalakis, Steven K. Herrine, Simona Rossi – 27 September 2007 – Human leukocyte antigen (HLA) compatibility has no clinically significant impact in cadaveric liver transplantation. Less is known regarding living‐donor liver transplantation (LDLT). Our prior analysis of the Organ Procurement and Transplantation Network (OPTN) database suggested a higher graft failure rate in patients who underwent LDLT from donors with close HLA match.

Acute liver failure in Spain: Analysis of 267 cases

Àngels Escorsell, Antoni Mas, Manuel de la Mata, Spanish Group for the Study of Acute Liver Failure – 27 September 2007 – The cause of acute liver failure (ALF) is a major determinant of its outcome. Acetaminophen (paracetamol) overdose is a leading cause of ALF in some developed countries, whereas in others, such as Spain, it is extremely rare. To analyze the etiology, characteristics, and outcome of ALF in Spain, we performed a retrospective analysis of 267 patients whom we observed from 1992 to 2000.

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