The liver in celiac disease

Alberto Rubio‐Tapia, Joseph A. Murray – 29 October 2007 – Celiac disease is a common (1% prevalence) chronic immune‐mediated disorder of the small intestine induced by dietary wheat, barley, and rye. Several hepatic disorders have been described in association with celiac disease. Isolated hypertransaminasemia with nonspecific histologic changes in a liver biopsy is the commonest hepatic presentation of celiac disease. A gluten‐free diet normalizes liver enzymes and histologic changes in most patients.

Modified Charlson Comorbidity Index for predicting survival after liver transplantation

Michael L. Volk, Jose C. Hernandez, Anna S. Lok, Jorge A. Marrero – 29 October 2007 – The benefit of liver transplantation (LT) is determined not only by the severity of illness, but also by the likelihood of posttransplantation survival. Current models are unable to accurately predict which patients will have the best posttransplant survival. We hypothesized that the Charlson Comorbidity Index (CCI), which includes nine comorbidities, could be used to predict survival after LT. We performed a retrospective study of 624 patients undergoing LT, with a median follow‐up time of 4.3 yr.

Use of splenic artery embolization to relieve tense ascites following liver transplantation in a patient with paroxysmal nocturnal hemoglobinuria

Charissa Y. Chang, Ashwani K. Singal, Sri V. Ganeshan, Thomas D. Schiano, Robert Lookstein, Sukru Emre – 29 October 2007 – Recurrent venous thrombosis following liver transplantation for Budd‐Chiari syndrome is common, particularly in the setting of an underlying myeloproliferative disorder. We describe a patient who developed refractory ascites due to portal vein thrombosis following liver transplantation for Budd‐Chiari syndrome in the setting of paroxysmal nocturnal hemoglobinuria.

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