Silvina E. Yantorno, Walter K. Kremers, Andrés E. Ruf, Julio J. Trentadue, Luis G. Podestá, Federico G. Villamil – 30 May 2007 – Assessment of prognosis in fulminant hepatic failure (FHF) is essential for the need and appropriate timing of orthotopic liver transplantation (OLT). In this study we investigated the prognostic efficacy of King's College criteria, Clichy's criteria, Model for End‐Stage Liver Disease (MELD), and Pediatric End‐Stage Liver Disease (PELD) in 120 consecutive patients with FHF.

Nimisha K. Parekh, Linda S. Hynan, James De Lemos, William M. Lee, Acute Liver Failure Study Group – 30 May 2007 – Although rare instances of cardiac injury or arrhythmias have been reported in acute liver failure (ALF), overall, the heart is considered to be spared in this condition. Troponin I, a sensitive and specific marker of myocardial injury, may be elevated in patients with sepsis and acute stroke without underlying acute coronary syndrome, indicating unrecognized cardiac injury in these settings.

Shridhar G. Iyer, Chao‐Long Chen, Chih‐Chi Wang, Shih‐Ho Wang, Allan M. Concejero, Yueh‐Wei Liu, Chin‐Hsiang Yang, Chee‐Chien Yong, Bruno Jawan, Yu‐Fan Cheng, Hock‐Liu Eng – 30 May 2007 – Liver transplantation (LT) may be indicated in glycogen storage disorders (GSD) when medical treatment fails to control the metabolic problems or when hepatic adenomas develop. We present our institutional experience with living donor LT (LDLT) for children with GSD. A total of 244 patients underwent primary LDLT at our institution from June 1994 to December 2005.

Mustapha Adham, Jérôme Dumortier, Amr Abdelaal, Pierre Sagnard, Catherine Boucaud, Olivier Boillot – 30 May 2007 – Preservation of the middle hepatic vein (MHV) for a right split liver transplantation (SLT) in an adult recipient is still controversial. The aim of this study was to evaluate the graft and patient outcomes after liver transplantation (LT) using a right split graft, according to the type of venous drainage. From February 2000 to May 2006, 33 patients received 34 cadaveric right split liver grafts.

Adel Bozorgzadeh, Mark Orloff, Peter Abt, Georgios Tsoulfas, Durald Younan, Randeep Kashyap, Ashok Jain, Parvez Mantry, Benedict Maliakkal, Alok Khorana, Seymour Schwartz – 30 May 2007 – The incidence of hepatocellular carcinoma (HCC) is on the rise worldwide as the most common primary hepatic malignancy. In the US approximately one half of all HCC is related to Hepatitis C virus (HCV) infection. The relationship between the primary disease and HCC recurrence after liver transplantation is unknown.

Jun‐Li Liu, Wei Cui – 30 May 2007

Zhaorui Lian, Jie Liu, Mengchao Wu, Hong‐Yang Wang, Patrick Arbuthnot, Michael Kew, Mark A. Feitelson – 30 May 2007 – Hepatitis B x antigen (HBxAg) is a trans‐activating protein that contributes to liver cancer, in part, by altering the expression of cellular genes. However, few natural effectors of HBxAg have been identified. Hence, HBxAg positive and negative HepG2 cells were prepared and analyzed by PCR select cDNA subtraction.

Winnie Yeo, Frankie K. F. Mo, Stephen L. Chan, Nancy W. Y. Leung, Pun Hui, Wai‐Yip Lam, Tony S. K. Mok, Kowk C. Lam, Wing M. Ho, Jane Koh, Julian W. Tang, Anthony T. Chan, Paul K. S. Chan – 30 May 2007 – HCC is a common cause of morbidity and mortality. For patients who are not candidates for curative surgery, systemic chemotherapy is one of the standard treatments. In parts of China and the Far East, over 80% of HCC patients have chronic HBV infection. In this study, we aimed to assess the relationship between pre‐chemotherapy HBV viral load and the survival of HCC patients.

Peter Jelnes, Eric Santoni‐Rugiu, Morten Rasmussen, Susanne Lunøe Friis, Jens Høiriis Nielsen, Niels Tygstrup, Hanne Cathrine Bisgaard – 30 May 2007 – The experimental protocols used in the investigation of stem cell–mediated liver regeneration in rodents are characterized by activation of the hepatic stem cell compartment in the canals of Hering followed by transit amplification of oval cells and their subsequent differentiation along hepatic lineages.

Neeraj Saraf, M. Isabel Fiel, Graciela DeBoccardo, Sukru Emre, Thomas D. Schiano – 30 May 2007 – Early histological recurrence of hepatitis C after liver transplantation (LT) has a negative impact on patient and graft survival. We report a case of histological recurrence of HCV occurring in the second week after LT. A 75‐year‐old woman with chronic HCV and hepatocellular carcinoma underwent LT with an organ from a 75‐year‐old HCV‐negative deceased donor.