Wei‐Hong Wen, Jia‐Yun Liu, Wei‐Jun Qin, Jing Zhao, Tao Wang, Lin‐Tao Jia, Yan‐Ling Meng, Hui Gao, Cai‐Fang Xue, Bo‐Quan Jin, Li‐Bo Yao, Si‐Yi Chen, An‐Gang Yang – 27 June 2007 – RNA interference is highly effective at inhibiting HBV gene expression and replication. However, before small interfering RNA (siRNA) can be used in the clinic, it is essential to develop a system to target their delivery. Antibody‐mediated delivery is a novel approach for targeting siRNA to appropriate cells. In this report, we asked whether this siRNA delivery strategy would be effective against HBV.

Ian Homer Y. Cua, Jason M. Hui, Priyanka Bandara, James G. Kench, Geoffrey C. Farrell, Geoffrey W. McCaughan, Jacob George – 27 June 2007 – The role of tumor necrosis factor α, interleukin 6, leptin, and adiponectin in the pathogenesis of hepatitis C virus (HCV)‐associated insulin resistance (IR) remains controversial.

Agnieszka Banas, Takumi Teratani, Yusuke Yamamoto, Makoto Tokuhara, Fumitaka Takeshita, Gary Quinn, Hitoshi Okochi, Takahiro Ochiya – 27 June 2007 – Recent observations indicate that several stem cells can differentiate into hepatocytes; thus, cell‐based therapy is a potential alternative to liver transplantation. The goal of the present study was to examine the in vitro hepatic differentiation potential of adipose tissue‐derived mesenchymal stem cells (AT‐MSCs).

Bommayya Narayanaswamy, Christopher Gonde, J. Michael Tredger, Munther Hussain, Diego Vergani, Mark Davenport – 27 June 2007 – Biliary atresia (BA) may be characterized as an occlusive cholangiopathy affecting both intra‐ and extra‐hepatic parts of the biliary tree, together with a pronounced inflammatory response consisting of hepatic infiltration of (predominantly) CD4+ lymphocytes and macrophages. Soluble cellular adhesion molecules are also known to be raised at the time of portoenterostomy, presumably reflecting intrahepatic disease.

Nathalie Ganne‐Carrié, Marianne Ziol, Victor de Ledinghen, Catherine Douvin, Patrick Marcellin, Laurent Castera, Daniel Dhumeaux, Jean‐Claude Trinchet, Michel Beaugrand – 27 June 2007

Ravi Jhaveri, Nancy Murray – 27 June 2007

Anna S. F. Lok, Brian J. McMahon – 27 June 2007

Jens H. Henriksen – 27 June 2007

Cara L. Mack – 27 June 2007

Johannes Herkel, Michael P. Manns, Ansgar W. Lohse – 27 June 2007