Ethanol and fish oil induce NFκB transactivation of the collagen α2(I) promoter through lipid peroxidation–driven activation of the PKC‐PI3K‐Akt pathway
Natalia Nieto – 30 May 2007 – To analyze whether fish oil, as a source of polyunsaturated fatty acids from the n‐3 series, could synergize with ethanol to promote collagen I upregulation in vivo, collagen α2(I) promoter‐βGal (COL1A2‐βGal) transgenic mice were fed a diet enriched in fish oil in the presence of ethanol (ethanol group) or dextrose (control group).