Preserving renal function in liver transplant recipients with rabbit anti‐thymocyte globulin and delayed initiation of calcineurin inhibitors

Iman Bajjoka, Lama Hsaiky, Kimberly Brown, Marwan Abouljoud – 27 December 2007 – Early renal dysfunction following liver transplantation is associated with increased morbidity and mortality. To evaluate the impact of delayed initiation of calcineurin inhibitor on renal function, we conducted a retrospective study comparing 118 liver transplant recipients who received rabbit anti‐thymocyte globulin and delayed initiation of calcineurin inhibitor with 80 liver transplant recipients who received no antibody and early initiation of calcineurin inhibitor (control group).

Platelet count is not a predictor of the presence or development of gastroesophageal varices in cirrhosis

Amir A. Qamar, Norman D. Grace, Roberto J. Groszmann, Guadalupe Garcia‐Tsao, Jaime Bosch, Andrew K. Burroughs, Rie Maurer, Ramon Planas, Angels Escorsell, Juan Carlos Garcia‐Pagan, David Patch, Daniel S. Matloff, Robert Makuch, Portal Hypertension Collaborative Group – 27 December 2007 – Current guidelines recommend esophagogastroduodenoscopy (EGD) in patients with cirrhosis to screen for gastroesophageal varices (GEV). Thrombocytopenia has been proposed as a noninvasive test to predict the presence of GEV.

Human herpesvirus 6 infection in adult living related liver transplant recipients

Masahiro Ohashi, Ken Sugata, Masaru Ihira, Yoshizo Asano, Hiroto Egawa, Yasutsugu Takada, Shinji Uemoto, Tetsushi Yoshikawa – 27 December 2007 – To analyze human herpesvirus 6 (HHV‐6) infection in adult living related liver transplantation, we performed a virological analysis, including viral isolation, serological assay, and real‐time polymerase chain reaction, of serially collected blood samples from 67 recipients. In addition, cytokine levels were measured to determine their role in viral reactivation.

Predicting immunosuppressant dosing in the early postoperative period with noninvasive indocyanine green elimination following orthotopic liver transplantation

Brian M. Parker, Jacek B. Cywinski, Joan M. Alster, Samuel A. Irefin, Marc Popovich, Michael Beven, John J. Fung – 27 December 2007 – Twenty adult patients undergoing orthotopic liver transplantation (OLT) were enrolled in this study, with the noninvasive indocyanine green plasma disappearance rate (ICG‐PDR) measured both during and after OLT to assess the relationship between ICG‐PDR and the ability of patients to achieve therapeutic postoperative tacrolimus immunosuppressant blood levels.

Subscribe to