Nonanastomotic biliary strictures after liver transplantation, part 1: Radiological features and risk factors for early vs. Late presentation

Carlijn I. Buis, Robert C. Verdonk, Eric J. Van der Jagt, Christian S. van der Hilst, Maarten J. H. Slooff, Elizabeth B. Haagsma, Robert J. Porte – 24 April 2007 – Nonanastomotic biliary strictures (NAS) are a serious complication after orthotopic liver transplantation (OLT). The exact pathogenesis is unclear. Purpose of this study was to identify risk factors for the development of NAS after OLT. A total of 487 adult liver transplants with a median follow‐up of 7.9 years were studied. All imaging studies of the biliary tree were reviewed.

Nonanastomotic biliary strictures after liver transplantation, part 2: Management, outcome, and risk factors for disease progression

Robert C. Verdonk, Carlijn I. Buis, Eric J. van der Jagt, Annette S. H. Gouw, Abraham J. Limburg, Maarten J. H. Slooff, Jan H. Kleibeuker, Robert J. Porte, Elizabeth B. Haagsma – 24 April 2007 – Nonanastomotic biliary strictures (NAS) after orthotopic liver transplantation (OLT) are associated with high retransplant rates. The aim of the present study was to describe the treatment of and identify risk factors for radiological progression of bile duct abnormalities, recurrent cholangitis, biliary cirrhosis, and retransplantation in patients with NAS.

Perioperative coagulation management in a patient with afibrinogenemia undergoing liver transplantation

Ralph J. Fuchs, Jay Levin, Meghan Tadel, William Merritt – 24 April 2007 – Afibrinogenemia is a rare hereditary coagulation disorder characterized by a propensity toward bleeding. A 21‐year‐old Hispanic woman with afibrinogenemia developed ascites, a distended abdomen, an enlarged liver, scleral icterus, and umbilical vein and abdominal wall vein distension. Computed tomography (CT) scan showed occlusion of the hepatic veins and the infrahepatic vena cava consistent with Budd‐Chiari syndrome.

Urinary ethyl glucuronide testing detects alcohol consumption in alcoholic liver disease patients awaiting liver transplantation

Yesim Erim, Michael Böttcher, Uta Dahmen, Olof Beck, Christoph E. Broelsch, Anders Helander – 24 April 2007 – This study compared measurement of urinary ethyl glucuronide (EtG), a conjugated minor ethanol metabolite with a longer detection window than ethanol itself, with breath alcohol testing and self‐report as ways to disclose recent drinking by 18 liver transplant candidates with an alcoholic liver disease diagnosis that underwent an addiction group therapy program.

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