Noninvasive monitoring of cerebral perfusion pressure in patients with acute liver failure using transcranial doppler ultrasonography
Shushma Aggarwal, David M. Brooks, Yoogoo Kang, Peter K. Linden, John F. Patzer – 25 June 2008 – Elevated intracranial pressure (ICP) leads to loss of cerebral perfusion, cerebral herniation, and irreversible brain damage in patients with acute liver failure (ALF). Conventional techniques for monitoring ICP can be complicated by hemorrhage and infection. Transcranial doppler ultrasonography (TCD) is a noninvasive device which can continuously measure cerebral blood flow velocity, producing a velocity‐time waveform that indirectly monitors changes in cerebral hemodynamics, including ICP.