Performance of the new MELD‐Na score in predicting 3‐month and 1‐year mortality in chinese patients with chronic hepatitis B

Vincent Wai‐Sun Wong, Angel Mei‐Ling Chim, Grace Lai‐Hung Wong, Joseph Jao‐Yao Sung, Henry Lik‐Yuen Chan – 30 August 2007 – The new Model for End‐Stage Liver Disease (MELD)‐Na score has been validated in a population predominantly affected by chronic hepatitis C and alcoholic liver disease. We aimed to validate the score in Chinese patients with chronic hepatitis B–related complications admitted to the hospital from 1996 to 2003.

Actin‐free Gc globulin: A rapidly assessed biomarker of organ dysfunction in acute liver failure and cirrhosis

Charalambos G. Antoniades, Philip A. Berry, Matthew Bruce, Timothy J.S. Cross, Andrew J. Portal, Munther J. Hussain, William Bernal, Julia A. Wendon, Diego Vergani – 30 August 2007 – Reductions in serum levels of Gc globulin, a hepatically synthesized component of the extracellular actin scavenger system responsible for complexing circulating actin and attenuating intravascular microthrombus formation, are associated with poor outcome in acute liver failure. Clinically applicable assays of the important actin‐free fraction (Af‐Gc) have not been available until now.

Retransplantation for hepatitis C: Results of a U.S. multicenter retransplant study

Timothy McCashland, Kymberly Watt, Elizabeth Lyden, Leon Adams, Michael Charlton, Alastair D. Smith, Brendan M. McGuire, Scott W. Biggins, Guy Neff, James R. Burton, Hugo Vargas, John Donovan, James Trotter, Thomas Faust – 30 August 2007 – It is widely perceived that outcomes are relatively poor following retransplantation (reTX) for recurrent of hepatitis C virus (HCV) infection. Transplant centers debate the utility of offering another liver to these patients. A U.S.

Employment and quality of life in liver transplant recipients

Sammy Saab, Cristina Wiese, Ayman B. Ibrahim, Lisette Peralta, Francisco Durazo, Steven Han, Hasan Yersiz, Douglas G. Farmer, R. Mark Ghobrial, Leonard I. Goldstein, Myron J. Tong, Ronald W. Busuttil – 30 August 2007 – The purposes of liver transplantation (LT) include the extension of survival, improvement in quality of life, and the return of the recipient as a contributing member of society. Employment is one measure of the ability to return to society. The aim of this study is to determine the factors affecting employment/subemployment after LT.

Twenty years of liver transplantation for Budd‐Chiari syndrome: A national registry analysis

Dorry L. Segev, Geoffrey C. Nguyen, Jayme E. Locke, Christopher E. Simpkins, Robert A. Montgomery, Warren R. Maley, Paul J. Thuluvath – 30 August 2007 – Several treatment options exist for the management of Budd‐Chiari syndrome (BCS), yet the relative role and timing of liver transplantation (LT) remain poorly defined. Small case series published to date have not been able to delineate the impact of comorbidities and thromboembolic complications of BCS on survival after LT.

Predictive value of actin‐free Gc‐globulin in acute liver failure

Frank V. Schiødt, Kristian Bangert, A. Obaid Shakil, Timothy McCashland, Natalie Murray, J. Eileen Hay, William M. Lee – 30 August 2007 – Serum concentrations of the actin scavenger Gc‐globulin may provide prognostic information in acute liver failure (ALF). The fraction of Gc‐globulin not bound to actin is postulated to represent a better marker than total Gc‐globulin but has been difficult to measure.

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