Inflammation is an important determinant of levels of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine (ADMA) in acute liver failure

Rajeshwar P. Mookerjee, R. Neil Dalton, Nathan A. Davies, Stephen J. Hodges, Charles Turner, Roger Williams, Rajiv Jalan – 22 February 2007 – Acute liver failure (ALF) is characterized by rapid progressive organ failure and poor outcome. The pathophysiology of multiorgan dysfunction in ALF remains unclear but increased systemic inflammatory response is believed to be an important determining factor. Asymmetric dimethylarginine (ADMA), an endogenous nitric oxide synthase inhibitor, results from proteolysis and the liver is a major site for its metabolism.

De novo esophageal neoplasia after liver transplantation

Sabine J. Presser, Guido Schumacher, Ruth Neuhaus, Peter Thuss‐Patience, Jens Stieler, Peter Neuhaus – 22 February 2007 – The purpose of the study was to determine the incidence, risk factors, treatment, and influence on survival of patients with de novo esophageal cancer after liver transplantation (LT). From 1988 to 2006, 1,926 patients underwent LT in our institution. A total of 9 patients (0.5%) developed a de novo esophageal cancer and 1 patient a cancer of the cardia (0.05%).

Subscribe to