Hyung Joon Yim, Munira Hussain, Ying Liu, Stephen N. Wong, Scott K. Fung, Anna S. F. Lok – 29 August 2006 – Multi‐drug resistant hepatitis B virus (HBV) has been reported in hepatitis B patients who received sequential antiviral therapy. In vitro studies showed that HBV constructs with mutations resistant to lamivudine and adefovir have marked reduction in sensitivity to combination of lamivudine and adefovir, whereas constructs with mutations resistant to either drug remain sensitive to the other drug.

Anaïs Vallet‐Pichard, Vincent Mallet, Stanislas Pol – 29 August 2006

Anneke Funk, Mouna Mhamdi, Heinz Hohenberg, Hans Will, Hueseyin Sirma – 29 August 2006 – Entry and intracellular transport of hepatitis B viruses have several unusual, largely unknown aspects. In this study, we explored the mode of virus entry using the duck hepatitis B virus (DHBV) and the primary hepatocyte infection model. Upon internalization, viral particles were enriched in an endosomal compartment, as revealed by biochemical and ultrastructural analysis. Virus‐containing vesicles harbored early endosome markers.

Gary L. Davis – 24 August 2006

Maureen M. J. Guichelaar, Rebecca Kendall, Michael Malinchoc, J. Eileen Hay – 24 August 2006 – Fracturing after liver transplantation (OLT) occurs due to the combination of preexisting low bone mineral density (BMD) and early posttransplant bone loss, the risk factors for which are poorly defined.

Sheung Tat Fan – 24 August 2006

Thomas D. Schiano, Michael Charlton, Zobair Younossi, Eithan Galun, Timothy Pruett, Ran Tur‐Kaspa, Rachel Eren, Shlomo Dagan, Neil Graham, Paulette V. Williams, John Andrews – 24 August 2006 – A randomized, double‐blind, dose‐escalation study evaluated the safety and efficacy of hepatitis C virus (HCV)‐AbXTL68, a neutralizing, high‐affinity, fully human, anti‐E2 monoclonal antibody, in 24 HCV‐positive patients undergoing liver transplantation.

Wolfram Karges, Christian Trautwein – 24 August 2006

Cüneyt Aytekin, Fatih Boyvat, Uğur Yılmaz, Ali Harman, Mehmet Haberal – 24 August 2006 – In liver transplant recipients, the treatment of a biliary leak resulting from anastomotic disruption usually requires surgical intervention. However, reoperation results in significant morbidity in such patients, whose clinical status may preclude a second surgery. Restoring the integrity of a disrupted biliary anastomosis can be difficult, and in some patients with that complication, neither the percutaneous technique nor the endoscopic approach effectively stents the biliary anastomosis.

Giuliano Testa, Massimo Malagò, Marian Porubsky, Marin Marinov, Howard Sankary, José Oberholzer, Silvio Nadalin, Enrico Benedetti – 24 August 2006 – The division of the hepatic duct is one of the most challenging passages of the donor hepatectomy. We report our experience with the early division, prior to the liver parenchyma resection, of the hepatic duct and the definition of the biliary anatomy with a probe inserted in the proper hepatic duct. From February 2002 to December 2004, 40 donors (25 male, 15 female; mean age 34, range 20‐57) underwent right hepatectomy.