The renal‐sparing efficacy of basiliximab in adult living donor liver transplantation

Chih‐Che Lin, Feng‐Rong Chuang, Chih‐Hsiung Lee, Chih‐Chi Wang, Yaw‐Sen Chen, Yueh‐Wei Liu, Bruno Jawan, Chao‐Long Chen – 23 September 2005 – The purpose of this study is to find out whether basiliximab administration will improve postoperative renal function by delaying the start of tacrolimus and decreasing of dosage requirement for tacrolimus in adult living donor liver transplantation (LDLT). Forty‐five adult LDLT recipients were enrolled in the study.

Inflammatory responses in a new mouse model of prolonged hepatic cold ischemia followed by arterialized orthotopic liver transplantation

Xiu‐Da Shen, Feng Gao, Bibo Ke, Yuan Zhai, Charles R. Lassman, Sei‐Ichiro Tsuchihashi, Douglas G. Farmer, Ronald W. Busuttil, Jerzy W. Kupiec‐Weglinski – 23 September 2005 – The current models of liver ischemia/reperfusion injury (IRI) in mice are largely limited to a warm ischemic component. To investigate the mechanism of hepatic “cold” IRI, we developed and validated a new mouse model of prolonged cold preservation followed by syngeneic orthotopic liver transplantation (OLT).

Early hepatic stellate cell activation is associated with advanced fibrosis after liver transplantation in recipients with hepatitis C

Mark W. Russo, Roberto J. Firpi, David R. Nelson, Robert Schoonhoven, Roshan Shrestha, Michael W. Fried – 23 September 2005 – Recurrent hepatitis C after liver transplantation is a serious problem faced by liver transplant recipients. Activation of hepatic stellate cells is an early step in hepatic fibrogenesis. The aim of this study was to evaluate hepatic stellate cell activation, early after liver transplantation, as a predictor for the subsequent development of advanced fibrosis.

Liver transplantation for adult patients with hepatocellular carcinoma in Korea: Comparison between cadaveric donor and living donor liver transplantations

Shin Hwang, Sung‐Gyu Lee, Jae‐Won Joh, Kyung‐Suk Suh, Dong‐Goo Kim – 23 September 2005 – Current selection criteria of liver transplantation (LT) for patients with hepatocellular carcinoma (HCC) were derived from the outcomes of cadaveric donor LT (CDLT). We tried to assess the applicability of such criteria to living donor LT (LDLT) through a comparative study between CDLT and LDLT. We analyzed the outcomes of 312 HCC patients who underwent LT at 4 Korean institutions during 1992 to 2002.

Orthotopic liver transplantation for biliary atresia: The U.S. experience

Neal R. Barshes, Timothy C. Lee, Rajesh Balkrishnan, Saul J. Karpen, Beth A. Carter, John A. Goss – 23 September 2005 – Biliary atresia is the most common indication for orthotopic liver transplantation (OLT) in the pediatric population. The outcomes of liver transplantation for biliary atresia, however, have not been formally examined on a national scale. The objective of this study was to identify pretransplant variables that predict patient survival after primary liver transplantation for biliary atresia.

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