Cerebral hemodynamic and metabolic profiles in fulminant hepatic failure: Relationship to outcome
Shushma Aggarwal, Walter Obrist, Howard Yonas, David Kramer, Yoogoo Kang, Victor Scott, Raymond Planinsic – 19 October 2005 – The purpose of this retrospective study was to examine the potential role of cerebral hemodynamic and metabolic factors in the outcome of patients with fulminant hepatic failure (FHF). Based on the literature, a hypothetical model was proposed in which physiologic changes progress sequentially in five phases, as defined by intracranial pressure (ICP) and cerebral blood flow (CBF) measurements.