Oxygenation during hypothermic rat liver preservation: An in vitro slice study to demonstrate beneficial or toxic oxygenation effects

Nils A. 't Hart, Arjan van der Plaats, Alexander Faber, Henri G.D. Leuvenink, Peter Olinga, Janneke Wiersema‐Buist, Gijsbertus J. Verkerke, Gerhard Rakhorst, Rutger J. Ploeg – 19 October 2005 – Hypothermic machine perfusion (HMP) of abdominal organs is shown to be superior compared to cold storage. However, the question remains if oxygenation is required during preservation as oxygen is essential for energy resynthesis but also generates toxic reactive oxygen species (ROS).

Neonatal hemochromatosis — medical treatment vs. transplantation: The king's experience

Fernanda Rodrigues, Marcia Kallas, Ruth Nash, Paul Cheeseman, Lorenzo D'Antiga, Mohamed Rela, Nigel D. Heaton, Giorgina Mieli‐Vergani – 19 October 2005 – The aim of our study was to compare the outcome of medical treatment vs. liver transplantation in infants with neonatal hemochromatosis (NH) referred to King's College Hospital from 1990‐2002. We conducted a retrospective review of 19 children from 14 families. Fifteen children presented at birth and 4 during the first week of life. One child was diagnosed by cordocentesis at 30 weeks of gestation.

Living donor liver transplantation for biliary atresia complicated by situs inversus: Technical highlights

Kentaro Matsubara, Yasuhiro Fujimoto, Hideya Kamei, Kohei Ogawa, Mureo Kasahara, Mikiko Ueda, Hiroto Egawa, Yasutsugu Takada, Masaki Kitajama, Koichi Tanaka – 19 October 2005 – Living‐donor liver transplantation (LDLT) has become an established technique to treat children with end‐stage liver disease. Biliary atresia (BA), one of the most common indications for liver transplantation in children, can be associated with situs inversus (SI). In the past, the presence of SI has been considered to be an absolute contraindication for liver transplantation because of the technical difficulties.

Feasibility of using the cystic duct for biliary reconstruction in right‐lobe living donor liver transplantation

Katsuhiro Asonuma, Hideaki Okajima, Mikako Ueno, Takayuki Takeichi, Manuel E. Zeledon Ramirez, Yukihiro Inomata – 19 October 2005 – Duct‐to‐duct biliary reconstruction has been introduced in adult living donor liver transplantation (LDLT). In right‐lobe grafts, however, the presence of two or three separated bile duct orifices is not rare and makes an alternative approach for reconstruction necessary. We used the cystic duct for one of the anastomoses in biliary reconstruction for 5 right‐lobe living donor liver transplants with two separated ducts.

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