Langerhans' cell histiocytosis after living donor liver transplantation: Report of a case

Ryoko Honda, Yasuharu Ohno, Takuya Iwasaki, Sadayuki Okudaira, Masahiko Okada, Akira Kamitamari, Koichi Ohshima, Hiroyuki Moriuchi, Takashi Kanematsu – 19 October 2005 – We report a case of Langerhans' cell histiocytosis (LCH) occurring after a living donor liver transplantation (LDLT) for fulminant hepatitis. A 9‐month‐old girl underwent an LDLT for fulminant hepatitis of an unknown cause. The histology of the native liver did not show any findings of LCH. On postoperative day 42, her Epstein‐Barr virus (EBV)‐DNA and cytomegalovirus antigenemia were both found to be positive.

Pretransplant survival is shorter in HIV‐positive than HIV‐negative subjects with end‐stage liver disease

Margaret V. Ragni, Bijan Eghtesad, Kimberly W. Schlesinger, Igor Dvorchik, John J. Fung – 19 October 2005 – Despite improved survival after liver transplantation (OLTX) in HIV‐positive individuals treated with highly active antiretroviral therapy (HAART), some transplant candidates do not survive to OLTX. To determine if pretransplant outcome is related to severity of liver disease and/or HIV infection, we prospectively evaluated 58 consecutive HIV‐positive candidates seen at a single center from 1997‐2002.

Oxygenation during hypothermic rat liver preservation: An in vitro slice study to demonstrate beneficial or toxic oxygenation effects

Nils A. 't Hart, Arjan van der Plaats, Alexander Faber, Henri G.D. Leuvenink, Peter Olinga, Janneke Wiersema‐Buist, Gijsbertus J. Verkerke, Gerhard Rakhorst, Rutger J. Ploeg – 19 October 2005 – Hypothermic machine perfusion (HMP) of abdominal organs is shown to be superior compared to cold storage. However, the question remains if oxygenation is required during preservation as oxygen is essential for energy resynthesis but also generates toxic reactive oxygen species (ROS).

Neonatal hemochromatosis — medical treatment vs. transplantation: The king's experience

Fernanda Rodrigues, Marcia Kallas, Ruth Nash, Paul Cheeseman, Lorenzo D'Antiga, Mohamed Rela, Nigel D. Heaton, Giorgina Mieli‐Vergani – 19 October 2005 – The aim of our study was to compare the outcome of medical treatment vs. liver transplantation in infants with neonatal hemochromatosis (NH) referred to King's College Hospital from 1990‐2002. We conducted a retrospective review of 19 children from 14 families. Fifteen children presented at birth and 4 during the first week of life. One child was diagnosed by cordocentesis at 30 weeks of gestation.

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