28 November 2005

Philippe Ichai, Anne Marie Roque Afonso, Mylène Sebagh, Maria Eugenia Gonzalez, Liana Codés, Daniel Azoulay, Faouzi Saliba, Vincent Karam, Elisabeth Dussaix, Catherine Guettier, Denis Castaing, Didier Samuel – 28 November 2005 – We report 5 cases of acute liver failure related to herpes simplex (HSV) infection in 1 immunocompetent and 4 immunosuppressed patients. One patient was too ill for liver transplantation indication. Three patients, among the 4 listed, underwent liver transplantation.

T. Clark Gamblin, David A. Geller – 28 November 2005

Michal Carmiel‐Haggai, M. Isabel Fiel, Himabindu C. Gaddipati, Chaim Abittan, Sabera Hossain, Sasan Roayaie, Myron E. Schwartz, Gabriel Gondolesi, Sukru Emre, Thomas D. Schiano – 28 November 2005 – Retransplantation (re‐LT) of patients with recurrent hepatitis C virus (HCV) carries significant morbidity and mortality, negatively impacting on an already scarce donor allograft pool. In this study, we investigated the outcome of allografts and patients after re‐LT due to recurrent HCV. Between 1989 and 2002, 47 patients were retransplanted at our institution due to HCV‐related graft failure.

Tingbo Liang, Shiguo Xu, Jun Yu, Kezhen Shen, Donglin Li, Shusen Zheng – 28 November 2005 – Mitogen‐activated protein kinases (MAPK) play a pivotal role in ischemia reperfusion injuries of heart and liver, but the activation pattern of MAPKs in the early phase of different size liver isografts remains unclear. The experiment is designed to investigate the activation pattern and role of MAPKs in isografts of the rat with different size liver transplantation.

Josh Levitsky, Andre C. Kalil, Jane L. Meza, Glenn E. Hurst, Alison Freifeld – 28 November 2005 – Previous case series have reported serious complications of chicken pox (CP) after pediatric liver transplantation (PLT), mainly due to visceral dissemination. The goal of our study was to determine the incidence, risk factors, and outcomes of CP after PLT. A case‐control study of all CP infections in pediatric transplant recipients followed at our center from September 1993 to April 2004 was performed.

Javier Vaquero, Robert J. Fontana, Anne M. Larson, Nathan M.T. Bass, Timothy J. Davern, A. Obaid Shakil, Steven Han, M. Edwyn Harrison, Todd R. Stravitz, Santiago Muñoz, Robert Brown, William M. Lee, Andres T. Blei – 28 November 2005 – Monitoring of intracranial pressure (ICP) in acute liver failure (ALF) is controversial as a result of the reported complication risk (∼20%) and limited therapeutic options for intracranial hypertension.

Matthew Hoare, William T.H. Gelson, Susan E. Davies, Martin Curran, Graeme J.M. Alexander – 28 November 2005 – Schistosomiasis affects 200 to 250 million people worldwide. Hepatic schistosomiasis is a well‐recognized cause of chronic liver disease and portal hypertension. There are no previous reports of schistosomiasis post liver transplantation. We report on 2 cases of schistosomiasis in liver transplant recipients— a case of gastric schistosomiasis and a case of hepatic schistosomiasis.

Hidenori Haruta, Hironori Yamamoto, Koichi Mizuta, Yoshiaki Kita, Takeji Uno, Satoshi Egami, Shuji Hishikawa, Kentaro Sugano, Hideo Kawarasaki – 28 November 2005 – Biliary complications remain a major concern after living donor liver transplantation. We describe a pediatric case who underwent a successful endoscopic balloon dilatation of biliary‐enteric stricture following living donor liver transplantation using a newly developed method of enteroscopy. The 7‐year‐old boy with late biliary stricture of choledochojejunostomy was admitted 6 years after transplantation.

Claire Terry, Anil Dhawan, Ragai R. Mitry, Sharon C. Lehec, Robin D. Hughes – 28 November 2005 – Cryopreservation of human hepatocytes is important for the treatment of liver disease by hepatocyte transplantation and also for the use of hepatocytes as an in vitro model of the liver. One factor in the success of cryopreservation is the quality of cells before freezing.