HCV‐associated B cell clonalities in the liver do not carry the t(14;18) chromosomal translocation

Domenico Sansonno, Felicia Anna Tucci, Valli De Re, Gianfranco Lauletta, Michele Montrone, Massimo Libra, Franco Dammacco – 25 October 2005 – Infection with HCV can be associated with B‐cell non‐Hodgkin lymphoma. Polymerase chain reaction (PCR) amplification assays for Bcl‐2/IgH rearrangement were performed on nucleic acids extracted from portal tract inflammatory infiltrates, isolated with laser capture microdissection (LCM), from liver biopsy sections of 16 hepatitis C virus (HCV)‐infected patients with and without extrahepatic B cell–related disorders.

Langerhans' cell histiocytosis after living donor liver transplantation: Report of a case

Ryoko Honda, Yasuharu Ohno, Takuya Iwasaki, Sadayuki Okudaira, Masahiko Okada, Akira Kamitamari, Koichi Ohshima, Hiroyuki Moriuchi, Takashi Kanematsu – 19 October 2005 – We report a case of Langerhans' cell histiocytosis (LCH) occurring after a living donor liver transplantation (LDLT) for fulminant hepatitis. A 9‐month‐old girl underwent an LDLT for fulminant hepatitis of an unknown cause. The histology of the native liver did not show any findings of LCH. On postoperative day 42, her Epstein‐Barr virus (EBV)‐DNA and cytomegalovirus antigenemia were both found to be positive.

Pretransplant survival is shorter in HIV‐positive than HIV‐negative subjects with end‐stage liver disease

Margaret V. Ragni, Bijan Eghtesad, Kimberly W. Schlesinger, Igor Dvorchik, John J. Fung – 19 October 2005 – Despite improved survival after liver transplantation (OLTX) in HIV‐positive individuals treated with highly active antiretroviral therapy (HAART), some transplant candidates do not survive to OLTX. To determine if pretransplant outcome is related to severity of liver disease and/or HIV infection, we prospectively evaluated 58 consecutive HIV‐positive candidates seen at a single center from 1997‐2002.

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