Evangelos Cholongitas, Laura Marelli, Vibhakorn Shusang, Marco Senzolo, Keith Rolles, David Patch, Andrew K. Burroughs – 23 June 2006 – The Model for End‐Stage Liver Disease (MELD) score is now used for allocation in liver transplantation (LT) waiting lists, replacing the Child‐Turcotte‐Pugh (CTP) score. However, there is debate as whether it is superior to CTP score to predict mortality in patients with cirrhosis on the LT waiting list and after LT. We reviewed studies comparing the accuracy of MELD vs. CTP score in transplantation settings.

Jay H. Hoofnagle – 23 June 2006

Barbara Haber – 23 June 2006

Julia L. Newton, G. John Gibson, Mark Tomlinson, Katharine Wilton, David Jones – 23 June 2006 – A significant proportion of patients with primary biliary cirrhosis (PBC) suffer from severe fatigue. The aim of this study was to characterize patterns of daytime sleep in patients with PBC (using both objective and subjective assessment approaches) and to study the association between sleep abnormality and fatigue severity.

Ton Lisman, Tamara N. Bongers, Jelle Adelmeijer, Harry L.A. Janssen, Moniek P.M. de Maat, Philip G. de Groot, Frank W.G. Leebeek – 23 June 2006 – Cirrhosis of the liver is frequently accompanied by complex alterations in the hemostatic system, resulting in a bleeding tendency. Although many hemostatic changes in liver disease promote bleeding, compensatory mechanisms also are found, including high levels of the platelet adhesive protein von Willebrand Factor (VWF). However, conflicting reports on the functional properties of VWF in cirrhosis have appeared in literature.

Stuart J. Forbes, Malcolm R. Alison – 23 June 2006

James D. Perkins – 23 June 2006

Vincent T. Armenti – 23 June 2006

Marie‐Odile Serinet, Pierre Broué, Emmanuel Jacquemin, Alain Lachaux, Jacques Sarles, Frédéric Gottrand, Frédéric Gauthier, Christophe Chardot – 23 June 2006 – This study analyzed the results of the decentralized management of biliary atresia (BA) in France, where an improved collaboration between centers has been promoted since 1997. Results were compared to those obtained in England and Wales, where BA patients have been centralized in three designated centers since 1999.

MinDe Zeng, YiMin Mao, GuangBi Yao, Hao Wang, JinLin Hou, YaoZong Wang, Beulah N. Ji, Chai‐Ni P. Chang, Keith F. Barker – 23 June 2006 – Four hundred and eighty Chinese subjects with hepatitis B e antigen (HBeAg)–positive chronic hepatitis B (CHB) were enrolled in a multicenter, double‐blind, randomized, placebo‐controlled study of adefovir dipivoxil (ADV) 10 mg once daily.