Early perioperative death associated with reexpansion pulmonary edema during liver transplantation

Wagner C. Marujo, Flavio Takaoka, Rita M. A. Moura, Fernando L. Pandullo, Andre R. Morrone, Marcelo M. Linhares, Alexandre Teruya, Isaac Altikes – 19 October 2005 – Hydrothorax is a frequent finding in patients with end‐stage liver disease. During the hepatectomy phase of liver transplantation, it is often needed to evacuate large pleural effusions. The acute expansion of the collapsed lung can cause reexpansion pulmonary edema with variable clinical significance. However, this complication has rarely been reported after liver transplantation.

Comparison of cyclosporine microemulsion and tacrolimus in 39 recipients of living donor liver transplantation

Koichi Tanaka, John Lake, Federico Villamil, Gary Levy, Paul Marotta, Sergio Mies, Bernard de Hemptinne, Christian Moench – 19 October 2005 – New immunosuppressive agents and regimens should be evaluated specifically in living donor liver transplant patients due to potential clinical and pharmacokinetic differences between deceased donor and living donor transplant recipients.

Improved machine perfusion preservation of the non‐heart‐beating donor rat liver using polysol: A new machine perfusion preservation solution

Maud Bessems, Benedict M. Doorschodt, Jan van Marle, Heleen Vreeling, Alfred J. Meijer, Thomas M. van Gulik – 19 October 2005 – Waiting lists for transplantation have stimulated interest in the use of non‐heart‐beating donor (NHBD) organs. Recent studies on organ preservation have shown advantages of machine perfusion (MP) over cold storage (CS). To supply the liver with specific nutrients during MP, the preservation solution Polysol was developed. The aim of our study was to compare CS in University of Wisconsin solution (UW) with MP using UW‐gluconate (UW‐G) or Polysol in an NHBD model.

Mesogonadal shunts for extrahepatic portal vein thrombosis and variceal hemorrhage

Heung Bae Kim, James J. Pomposelli, Craig W. Lillehei, Roger L. Jenkins, Maureen M. Jonas, Laura E. Krawczuk, Steven J. Fishman – 19 October 2005 – Extrahepatic portal vein thrombosis (EHPVT) may occur in children or adults and usually comes to clinical attention due to complications of portal hypertension such as variceal hemorrhage. A variety of standard surgical techniques exist to manage these patients, but when these fail surgical options are limited. We describe two novel portosystemic shunts that utilize the gonadal vein as an autologous conduit.

Immunosuppression for liver transplantation in HCV‐infected patients: Mechanism‐based principles

Bijan Eghtesad, John J. Fung, Anthony J. Demetris, Noriko Murase, Roberta Ness, Debra C. Bass, Edward A. Gray, Obaid Shakil, Bridget Flynn, Amadeo Marcos, Thomas E. Starzl – 19 October 2005 – We retrospectively analyzed 42 hepatitis C virus (HCV)‐infected patients who underwent cadaveric liver transplantation under two strategies of immunosuppression: (1) daily tacrolimus (TAC) throughout and an initial cycle of high‐dose prednisone (PRED) with subsequent gradual steroid weaning, or (2) intraoperative antithymocyte globulin (ATG) and daily TAC that was later space weaned.

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