Daniel Azoulay, Antoinette Lemoine, Ashley Dennison, Jean Michel Gries, Isabelle Dolizy, Denis Castaing, Philippe Beaune, Henri Bismuth – 1 June 1993 – Despite the availability of whole‐blood cyclosporine assays, the different responses of individual patients to its administration after transplantation continue to pose clinical problems, particularly with respect to toxicity. Fifty‐seven recipients of first orthotopic liver transplants were studied between January 1992 and July 1992.

Thomas E. Starzl, Anthony J. Demetris, Massimo Trucco, Noriko Murase, Camillo Ricordi, Suzanne Ildstad, Hector Ramos, Satoru Todo, Andreas Tzakis, John J. Fung, Michael Nalesnik, Adriana Zeevi, William A. Rudert, Mirjana Kocova – 1 June 1993

1 June 1993

Nobukazu Yuki, Norio Hayashi, Hideki Hagiwara, Tetsuo Takehara, Kazuhiro Katayama, Akinori Kasahara, Hideyuki Fusamoto, Takenobu Kamada – 1 June 1993 – We quantified IgG antibodies to structural (core) and nonstructural (C100‐3) hepatitis C virus proteins in 42 patients with chronic hepatitis C treated with a 6‐mo course of interferon‐α Sera were drawn before and at the end of therapy and also 6 mo after therapy withdrawal; they were stored for later analysis of antibodies and serum hepatitis C virus RNA.

Emilio Rocchi, Marco Cassanelli, Athos Borghi, Franco Paolillo, Marcello Pradelli, Giovanna Casalgrandi, Aldo Burani, Ennio Gallo – 1 June 1993 – The need for accurate and noninvasive evaluation of liver iron stores prompted us to evaluate the reliability of high‐field magnetic resonance imaging equipment in liver patients with low or moderate siderosis, given the poor results obtained using systems operating at low field strength in such cases.

Raymond S. Koff – 1 June 1993

1 June 1993

Kenji Ikeda, Satoshi Saitoh, Isao Koida, Akihito Tsubota, Yasuji Arase, Kazuaki Chayama, Hiromitsu Kumada – 1 June 1993 – To clarify the angiographic features of small hepatocellular carcinoma, we performed digital subtraction angiography in 91 patients with hepatocellular carcinomas of 2 cm or less. Repeated digital subtraction angiography studies were performed in 25 patients whose first angiograms showed no tumor staining. Digital subtraction angiography showed hypervascular tumor staining in only 51 patients (56.0%).

Peter Donaldson, James Underhill, Derek Doherty, Karen Hayllar, Roy Calne, Kai‐Chah Tan, John O'Grady, Derek Wight, Bernard Portmann, Roger Williams – 1 June 1993 – To date only one published large series of human leukocyte antigen matching and liver allograft survival exists, and considerable confusion has arisen about the advantage or disadvantage of human leukocyte antigen matching.

John Koskinas, Vivienne R. Winrow, George L. A. Bird, Johnson Y. N. Lau, Bernard C. Portmann, David R. Blake, Graeme J. M. Alexander, Roger Williams – 1 June 1993 – The precise mechanism of the pathogenesis of alcoholic hepatitis is unknown, but immune involvement may perpetuate and exacerbate the process. Heatshock proteins, normally protective, may be immunogenic and have been shown to induce antibody formation in some inflammatory conditions. Alcohol, cellular hypoxia and tumor necrosis factor, all involved in alcoholic hepatitis, are potent inducers of heatshock protein.