Successful endoscopic obturation of gastric varices with butyl cyanoacrylate

Marie‐Jose Ramond, Dominique Valla, Jean‐François Mosnier, Claude Degott, Jacques Bernuau, Bernard Rueff, Jean‐Pierre Benhamou – 1 October 1989 – In 27 patients who had bled from esophagogastric varices, large‐sized and/or actively bleeding gastric varices were endoscopically obturated with the tissue adhesive butyl cyanoacrylate. Active bleeding was stopped in six patients.

Replication of duck hepatitis B virus in primary duck hepatocytes and its dependence on the state of differentiation of the host cell

Peter R. Galle, Hans‐jürgen Schlicht, Christa Kuhn, Heinz Schaller – 1 October 1989 – Primary duck hepatocytes obtained from Pekin ducks congenitally infected with duck hepatitis B virus were used to monitor expression of viral proteins and replication of viral DNA in cell culture. Duck hepatitis B virus core antigen, duck hepatitis B virus pre‐surface antigen and duck hepatitis B virus DNA were detectable for at least 12 days after cell plating.

Taurocholate transport by basolateral plasma membrane vesicles isolated from human liver

Donald A. Novak, Frederick C. Ryckman, Frederick J. Suchy – 1 October 1989 – Transport of taurocholate into the hepatocyte against unfavorable chemical and electrical gradients occurs via a sodium‐dependent, carrier‐mediated transport system. Although this cotransporter has been characterized in the rodent, it has not been demonstrated in man. Therefore, we utilized human liver, obtained via multiorgan donation but not used for transplantation, to prepare basolateral (sinusoidal) liver plasma membrane vesicles by a Percoll gradient method.

A pilot, double‐blind, controlled 1‐year trial of prednisolone treatment in primary biliary cirrhosis: Hepatic improvement but greater bone loss

Harriet C. Mitchison, Margaret F. Bassendine, Archie J. Malcolm, Alex J. Watson, Christopher O. Record, Oliver F. W. James – 1 October 1989 – A randomized, double‐blind, 1‐year pilot study of prednisolone treatment for primary biliary cirrhosis was undertaken. Nineteen patients received 30 mg prednisolone per day initially, with a maintenance dose of 10 mg per day. Seventeen patients received placebo. The groups were matched for age, menopausal status, hepatic histological stage and bilirubin.

Aplastic anemia after liver transplantation for fulminant viral hepatitis: Black boX or bag of worms?

Jerome B. Zeldis – 1 October 1989 – Aplastic anemia developed in 9 of 32 patients (28 percent) undergoing orthotopic liver transplantation for acute non‐A, non‐B hepatitis, at one to seven weeks after the procedure. No patient previously had evidence of hematologic dysfunction or conditions known to be associated with aplastic anemia.

Bile acids inhibit endotoxin‐induced release of tumor necrosis factor by monocytes: An in Vitro study

Jan Willem Greve, Dirk J. Gouma, Wim A. Buurman – 1 October 1989 – Endotoxins play an important role in the pathogenesis of complications of surgery in obstructive jaundice. Preoperative treatment with orally administered deoxycholic acid prevented endotoxin‐related complications, such as renal malfunction. Other bile acids, however, were less effective, and the mechanism of action is not known.

Defective immunoregulation in primary biliary cirrhosis: CD4+, Leu–8+ T cells have abnormal activation and suppressor function in vitro

Takeaki Suou, Maria P. Civeira, Marjorie E. Kanof, Ricardo Moreno‐Otero, E. Anthony Jones, Stephen P. James – 1 October 1989 – To determine whether abnormalities of lymphocyte function in primary biliary cirrhosis are due to altered function of immunoregulatory T cell subpopulations, phenotypic and functional characteristics of CD4+ T cells were examined. The proportion of CD4+ T cells expressing the Leu‐8 and CD45R antigens was normal in patients with primary biliary cirrhosis.

Subscribe to