Paul C. Adams, Lawrie W. Powell, June W. Halliday – 1 July 1988 – A human hepatic ferritin receptor has been isolated from human liver and has been purified using affinity chromatography. An affinity constant of 6.0 × 108 moles−1 liter was determined for the ferritin receptor. The molecular weight was estimated to be approximately 53,000 by gel electrophoresis. Binding of ferritin to the receptor coupled to a microparticulate support was specific for human liver ferritin with no binding of rat or porcine ferritin.

Miren Zuriñe Ibarra, Ignacio Mora, Juan Antonio Quiroga, Javier Bartolomé, Faustino La Banda, Juan Carlos Porres, Vicente Carreño – 1 July 1988 – Antibody directed against HBsAg carries idiotypic determinants that may induce an autoantiidiotype antibody response. We describe a solid‐phase radioimmunoassay which allows specific detection of either IgG or IgM antibody to antibody directed against HBsAg. Among 138 chronic hepatitis B virus carriers, IgG autoantiidiotype was detected in 98 (71%) and IgM autoantiidiotype in 110 (80%).

Jaime Bosch, Josep M. Bordas, Ricardo Mastai, David Kravetz, Miquel Navasa, Jaime Chesta, M. Pilar Pizcueta, Juan C. García‐Pagán, Joan Rodés – 1 July 1988 – The present study investigated to what extent measurements of wedged and free hepatic venous pressures adequately reflect the effects of vasopressin at the esophageal varices in patients with cirrhosis.

Thierry Poynard, Jean‐Pierre Pignon, Sylvie Naveau, Jean‐Claude Chaput, Claire Infante‐Rivard, Jean‐Pierre Villeneuve – 1 July 1988

M. Sawkat Anwer, Kathleen Nolan – 1 July 1988 – A pH‐stat method was used to characterize H+ efflux pathways in hepatocytes in order to determine if Na+/ H+ and Ca++/H+ exchange are involved in H+ efflux from hepatocytes under basal conditions and if cyclic AMP analogs affect Na+/H+ exchange. Total H+ efflux of freshly prepared hepatocytes ranged from 10 to 15 nmoles per min per mg protein. A part of total H+ efflux (35 to 50%) was dependent on extracellular Na+.

Agesilao D'Arienzo, Luigi Celentano, Alessandro Scuotto, Pasqualina Di Siervi, Vinicio Lombardi, Giovanni Squame, Gabriele Mazzacca – 1 July 1988 – In normal subjects, thallium‐201, administered per rectum, is taken up mainly by the liver (heart/liver ratio in normal subjects: 0.04 to 0.12). It has been claimed that an increased heart/liver ratio is suggestive of portal‐caval shunting and portal hypertension.

Luigi Accatino, Patricia Gavilan – 1 July 1988 – Phospholipids and bile acids, by virtue of their amphiphilic properties, can interact in nonpolar media forming “inverted” structures (micelles) which presumably have an hydrophilic core and might act as diffusional carriers (ionophores) of electrolytes across low dielectric constant media or lipid membranes.

Rebecca W. Van Dyke, Harlan E. Ives – 1 July 1988

Paul S. Lietman – 1 July 1988

Irmin Sternlieb – 1 July 1988 – Experience with liver transplantation for patients with Wilson's disease who have major neurological impairment is limited, and this report describes the results obtained in two such patients. The first was a 30‐year‐old man with a 14‐month history of hepatic and neurological impairment. In spite of treatment with d‐penicillamine, he developed increasing dysarthria, dysphagia, akinesia and rigidity of all four limbs, and required continuous nursing care.