An extrahepatic bile duct growth factor: In vivo effect and preliminary characterization
Joy H. Glaser, Rachel Morecki, Sheila Fallon‐Friedlander, Marshall S. Horwitz – 1 March 1987 – Rabbit sera injected intraperitoneally into BALB/c mice were noted to produce a considerable and selective enlargement of extrahepatic bile ducts. The gallbladder, intrahepatic ducts, liver and other organs showed no stimulaion of growth. Duct enlargement leading to widening of its outer diameter which, on average, was 3.6 times that of normal, was due entirely to an increased number of epithelial cells with prominent proliferation of intramural glandular components.