J. Michael Schiff, Sandra L. Huling, Albert L. Jones – 1 September 1986 – The degradation of asialoglycoproteins in hepatocytes has been well described in several animal models, but no direct evidence has yet been obtained for asialoglycoprotein processing in the primate liver. A double radiolabeling strategy was employed in the experiments described in this paper to evaluate the fate of asialoorosomucoid in the squirrel monkey. Intravenously injected asialoorosomucoid was taken up by the liver with a half‐time of 1 min.

Philippe Gaulard, Elie Serge Zafrani, Philippe Mavier, Francisco Dario Rocha, Jean‐Pierre Farcet, Marine Divine, Corinne Haioun, Yvon Pinaudeau – 1 September 1986 – Three cases of a peculiar form of peripheral T‐cell lymphoma presenting as predominant hepatic disease with splenomegaly are reported. The three patients had marked liver enlargement without lymphadenopathy; white blood cell count was normal, and modifications of hepatic tests were mild. In the three cases, the diagnosis of the lymphoma was mainly based on the results of hepatic morphological changes.

Jorge J. Gumucio, Maryann May, Caroline Dvorak, Jose Chianale, Veronica Massey – 1 September 1986 – The objective of this study was to isolate hepatocytes of the proximal half (Zones 1 and 2) or distal half (Zones 2 and 3) of the liver acinus.

Ellen Kahn, Fredric Daum, James Markowitz, Saul Teichberg, Lynn Duffy, Rita Harper, Harvey Aiges – 1 September 1986 – Liver biopsies and/or autopsy specimens from 17 children (ages 1 week to 5 years) with nonsyndromatic paucity of the interlobular bile ducts were studied by light and electron microscopy. Initial biopsies were obtained before 90 days of age from all patients, and two or more specimens were available from nine. No specific underlying condition was found in nine infants.

Tadashi Ikeda, Andrew M. L. Lever, Howard C. Thomas – 1 September 1986 – Ninety per cent of patients infected in adult life with the hepatitis B virus clear the virus completely and 10% develop chronic infection. There is evidence for the involvement of interferon in the clearance of acute hepatitis B virus infection.

Johannes Bircher – 1 September 1986

Claudio Tiribelli – 1 September 1986 – Since glucagon can hyperpolarize hepatic plasma membrane and stimulate biliary bile acid secretion in vitro, we studied the effect of glucagon on taurocholate uptake and its relationship to plasma membrane potential in isolated rat hepatocytes. [14C]Taurocholate uptake was linear through 1 min and contained a saturable sodium‐dependent and a nonsaturable sodium‐independent component, Km of taurocholate uptake by the sodium‐dependent system was 18.4 μM.

1 September 1986

William A. Shaver, Harshika Bhatt, Burton Combes – 1 September 1986 – Low values for serum alkaline phosphatase activity were observed early in the course of two patients with Wilson's disease presenting with the combination of severe liver disease and Coombs' negative acute hemolytic anemia.

Javier Ariza, Francisco Gudiol, Carlos Dolz, Javier Xiol, Josefina Liñares, Jorge Bosch, Roman Pallares – 1 September 1986 – To determine the efficacy of aztreonam in the treatment of spontaneous bacterial peritonitis in patients with hepatic cirrhosis, 14 patients (7 males, 7 females) with 16 Gram‐negative infective episodes (12 Escherichia coli and 4 Klebsiella pneumoniae) were treated with aztreonam infusions at doses of 1 gm per 8 hr for a planned 14‐day period. Ages ranged from 40 to 75 years with a mean of 57 ± 10 years.