Comparison of Dietary Protein with an Oral, Branched Chain‐Enriched Amino Acid Supplement in Chronic Portal‐Systemic Encephalopathy: A Randomized Controlled Trial

Douglas Horst, Norman D. Grace, Harold O. Conn, Eugene Schiff, Steven Schenker, Alfredo Viteri, David Law, Colin E. Atterbury – 1 March 1984 – A randomized study was conducted in 37 hospitalized patients at six cooperating hospitals in which protein‐intolerant cirrhotic patients were fed increasing amounts of either dietary protein or a branched‐chain enriched amino acid solution (BCAA) until they attained an intake of 80 gm protein per day or equivalent or until they developed stage 2 encephalopathy.

Metabolic Bone Disease in Alcoholic Cirrhosis: A Comparison of the Effect of Vitamin D2 25‐Hydroxyvitamin D, or Supportive Treatment

Sohrab A. Mobarhan, Robert M. Russell, Robert R. Recker, David B. Posner, Frank L. Iber, Pamela Miller – 1 March 1984 – In a study of 56 alcoholics with liver cirrhosis, 18 (32%) had decreased bone density and low levels of serum 25‐hydroxyvitamin D (25‐OH‐D) (<20 ng per ml).

Frequency of Papillary Dysfunction Among Cholecystectomized Patients

Simon Bar‐Meir, Zamir Halpern, Eithan Bardan, Tuvia Gilat – 1 March 1984 – Four hundred and fifty‐four consecutive patients who had had their gallbladder removed were interviewed to determine the presence of upper abdominal pain, increased serum alkaline phosphatase and/or serum amylase activity. Patients with unexplained upper abdominal pain and/or enzyme abnormalities were offered endoscopic retrograde cholangiopancreatography (ERCP) and manometric evaluations.

Induction of Taurocholate Release from Isolated Rat Hepatocytes in Suspension by α‐Adrenergie Agents and Vasopressin: Implications for Control of Bile Salt Secretion

David A. Gewirtz, Joyce K. Randolph, I. David Goldman – 1 March 1984 – Hepatocytes incubated with 25 μM. [3H]taurocholate rapidly deplete the extracellular medium of [3H]taurocholate and achieve a steady‐state level of intracellular bile salt within 15 min. Exposure of cells at steady state ith extracellular taurocholate to the catecholamines norepinephrine or epinephrine results in release of 3H from the cells into the incubation medium; the 3H released represents almost exclusively unmetabolized [3H]taurocholate.

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