Correspondence
Henry Gans, David Eberle – 1 March 1982
Henry Gans, David Eberle – 1 March 1982
Rosemarie L. Fisher, Deborah W. Anderson, James L. Boyer, Kamal Ishak, Gerald Klatskin, John M. Lachin, M. James Phillips, The Steering Committee, The National Cooperative Gallstone Study Group – 1 March 1982 – A sample of 126 patients with cholelithiasis was treated with chenodeoxycholic acid (CDCA) (375 or 750 mg g.d.) for 2 years. Hepatotoxicity was assessed by sequential light (LM) and electron microscopic (EM) analysis of liver biopsies obtained before and after 9 and 24 months of therapy.
Patrice Vic, Bernard Saint‐Aubert, Cecile Astre, Philippe Bories, Andree Bonardet, Bernard Descomps, Claude Humeau, Henri Joyeux – 1 March 1982
1 March 1982
Alan D. Attie, Ray C. Pittman, Daniel Steinberg – 1 March 1982
Stewart Sell, Hyam L. Leffert – 1 January 1982 – Analysis of liver from rats exposed to chemical hepatocarcinogens has led to a model that postulates sequential premalignant changes, culminating in hepatoma formation from neoplastic nodules. Several experimental protocols devised during the last quarter century have focused upon this lineage model. But proof that neoplastic nodules are the definitive premalignant lesions has not been achieved.
Humberto Reyes – 1 January 1982