Ferruccio Bonino, Bill Hoyer, Judith Nelson, Ronald Engle, Giorgio Verme, John Gerin – 1 September 1981 – Sera and liver biopsies from 30 Italian patients, carriers of HBsAg for at least 3 years, were examined for markers of hepatitis B virus (HBV) infection by serological assays and immunofluorescence. Biopsies were analyzed for HBcAg, HBsAg, and δ antigen by immunofluorescence; sera were assayed for HBsAg/anti‐HBs, HBcAg/anti‐HBc, HBeAg/anti‐HBe, δ/anti‐δ, HBV‐specific DNA polymerase activity and the presence of HBV DNA.

1 September 1981

Michael C. Kew – 1 July 1981

1 July 1981

Leslie Zieve – 1 July 1981

Giulio Marchesini, Marco Zoli, Angela Angiolini, Cristina Dondi, Francesco B. Bianchi, Emilio Pisi – 1 July 1981 – The rates of muscle protein breakdown, as estimated by the urinary excretion of 3‐methylhistidine, were assessed in 30 cirrhotics and 15 controls on a strictly controlled diet. 3‐Methylhistidine excretion was increased in cirrhotics irrespective of the etiology of the disease, and correlated with basal glucagon levels and with the insulin/glucagon ratio.

Patrick Y. Wong – 1 July 1981

Harold O. Conn – 1 July 1981

Serge Erlinger – 1 July 1981

John F. Gerkens, Paul V. Desmond, Steven Schenker, Robert A. Branch – 1 July 1981 – The pharmacokinetic disposition of lorazepam was investigated in sham‐operated anesthetized dogs, dogs with hepatic devascularization, and dogs with total splanchnic devascularization following i.v. administration of 0.3 mg per kg of the drug. In sham‐operated dogs, lorazepam distribution was extensive (100 ± 15.2 liters) and clearance approximated expected liver blood flow (971 ± 91 ml per min). Lorazepam glucuronide levels in plasma rose rapidly in the first hour and reached a plateau by 5 hr.