Effect of chronic alcohol intake on hepatic fibrosis and granulomas in marine schistosomiasis mansoni
Hector Orrego, Yedy Israel, Ian R. Crossley, Adel A. F. Mahmoud, Pierre A. Peters, George Varghese, Ian R. Wanless – 1 September 1981 – In consideration of the vast prevalence of schistosomiasis and heavy alcohol consumption in many parts of the world, the possibility of an interaction between these two conditions inducing liver disease was studied in mice infected with Schistosoma mansoni. Alcohol consumption significantly reduced by 25% the mean granuloma diameter and by about 60% the extent of fibrous tissue deposition determined chemically as hydroxyproline.